Multi-Center Adolescent Clavicle Fracture Trial: Operative Vs. Non-Operative Treatment

Description

Investigators from eight tertiary care, level 1 pediatric trauma centers have developed a protocol for the establishment of a formal, prospective multi-center adolescent clavicle registry, with designs for standardized radiographic assessment and the prospective collection of validated outcome measures and complications data, for all patients, ages 10-18, treated for clavicle shaft fractures, operatively and non-operatively. Eventually, the investigators would like to do comparative analysis for the operative and non-operative treatment arms, with additional sub-stratified analyses performed within these treatment arms by age and activity level. Among the primary goals of research projects stemming from the first arm of this registry, FACTS A, is to explore the hypothesis that non-operative treatment is associated with lower costs, greater safety, and equivalent or superior outcomes, compared with operative treatment, despite a national trend towards increasing surgical treatment. The second arm of the registry, FACTS B, will continue to investigate the same hypotheses, excluding cost outcomes, in patients only with completely displaced midshaft clavicle fractures.

Conditions

Clavicle Fracture

Study Overview

Study Details

Study overview

Investigators from eight tertiary care, level 1 pediatric trauma centers have developed a protocol for the establishment of a formal, prospective multi-center adolescent clavicle registry, with designs for standardized radiographic assessment and the prospective collection of validated outcome measures and complications data, for all patients, ages 10-18, treated for clavicle shaft fractures, operatively and non-operatively. Eventually, the investigators would like to do comparative analysis for the operative and non-operative treatment arms, with additional sub-stratified analyses performed within these treatment arms by age and activity level. Among the primary goals of research projects stemming from the first arm of this registry, FACTS A, is to explore the hypothesis that non-operative treatment is associated with lower costs, greater safety, and equivalent or superior outcomes, compared with operative treatment, despite a national trend towards increasing surgical treatment. The second arm of the registry, FACTS B, will continue to investigate the same hypotheses, excluding cost outcomes, in patients only with completely displaced midshaft clavicle fractures.

Prospective, Multi-Center Adolescent Clavicle Fracture Registry

Multi-Center Adolescent Clavicle Fracture Trial: Operative Vs. Non-Operative Treatment

Condition
Clavicle Fracture
Intervention / Treatment

-

Contacts and Locations

Oakland

University of California San Francisco Benioff Children's Hospital Oakland, Oakland, California, United States,

San Diego

Rady Children's Hospital, San Diego, California, United States,

Atlanta

Children's Healthcare of Atlanta, Atlanta, Georgia, United States,

Boston

Boston Children's Hospital, Boston, Massachusetts, United States, 02115

Ann Arbor

University of Michigan Medical Center, Ann Arbor, Michigan, United States,

Saint Louis

Washington University at St. Louis, Saint Louis, Missouri, United States,

Memphis

Campbell Clinic Orthopaedics, Memphis, Tennessee, United States,

Dallas

Texas Scottish Rite Hospital, Dallas, Texas, United States,

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

For general information about clinical research, read Learn About Studies.

Eligibility Criteria

  • * Aged 10-18
  • * Diagnosis of a primary diaphyseal clavicle fracture
  • * Fracture must be completely displaced
  • * Patient - BCH subjects must pursue follow-up at BCH main campus or Waltham must be 59 days or less from the primary fracture
  • * All study patients (across all sites) must agree to be contacted by a long-term follow-up coordinator based out of Boston Children's Hospital for long-term follow-up questions (out to the 2-year time point). This can/will be done via phone, mail, text message, and/or email.
  • * Pathological fracture
  • * Previous ipsilateral fracture
  • * Unable to fill out outcome collection forms
  • * Refusal to participate
  • * Underlying neurologic or neurocognitive disorder that affects UE function
  • * Underlying metabolic bone disorder (e.g. osteogenesis imperfecta) that significantly alters normal bone healing
  • * Unable to project injury X-ray films if treated initially at an institution that is not a member of this register

Ages Eligible for Study

10 Years to 18 Years

Sexes Eligible for Study

ALL

Accepts Healthy Volunteers

No

Collaborators and Investigators

Boston Children's Hospital,

Benton E Heyworth, MD, PRINCIPAL_INVESTIGATOR, Boston Children's Hospital

Study Record Dates

2026-06-01