RECRUITING

OCT in Fuchs' Dystrophy

Talk to us

Conditions

Fuchs DystrophyPseudophakic Bullous KeratopathyFuchsOptical Coherence Tomography (OCT)PBK

Quick Navigation

Study Overview

This clinical trial focuses on testing the efficacy of different digital interventions to promote re-engagement in cancer-related long-term follow-up care for adolescent and young adult (AYA) survivors of childhood cancer.

Description

This is an observational study using optical coherence tomography (OCT) technology to quantify corneal edema in Fuchs' endothelial dystrophy and predict refractive shift from resolving corneal edema after surgical treatments.

Official Title

Evaluating Corneal Edema in Fuchs' Endothelial Dystrophy Using Optical Coherence Tomography

Quick Facts

Study Start:2020-06-26
Study Completion:2026-06
Study Type:Not specified
Phase:Not Applicable
Enrollment:Not specified
Status:RECRUITING

Study ID

NCT04258787

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Ages Eligible for Study:18 Years
Sexes Eligible for Study:ALL
Accepts Healthy Volunteers:No
Standard Ages:ADULT, OLDER_ADULT
Inclusion CriteriaExclusion Criteria
  1. * Damaged or diseased corneal endothelium from Fuchs' or PBK
  2. * Willingness to commit to required study visits
  1. * Prior Endothelial Keratoplasty (EK) or any other surgery except uncomplicated cataract surgery
  2. * Presence of a condition that increases the probability for treatment failure (e.g., heavily vascularized cornea, uncontrolled uveitis)
  3. * Other primary endothelial dysfunction conditions (e.g., posterior polymorphous corneal dystrophy and congenital hereditary corneal dystrophy, iridocorneal endothelial syndrome)
  4. * Central sub-epithelial or stromal scarring that could impact post-operative clarity assessment
  5. * Peripheral anterior synechiae in the angle greater than 3 clock hours
  6. * Hypotony
  7. * Uncontrolled glaucoma
  8. * Visually significant optic nerve or macular pathology

Contacts and Locations

Study Contact

Humberto Martinez, COT
CONTACT
503-494-7712
martinhu@ohsu.edu
Denzil Romfh, OD
CONTACT
503-494-4351
romfhd@ohsu.edu

Principal Investigator

Winston Chamberlain, MD, PhD
PRINCIPAL_INVESTIGATOR
Oregon Health and Science University

Study Locations (Sites)

Oregon Health & Science University
Portland, Oregon, 97239
United States

Collaborators and Investigators

Sponsor: Oregon Health and Science University

  • Winston Chamberlain, MD, PhD, PRINCIPAL_INVESTIGATOR, Oregon Health and Science University

Study Record Dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Registration Dates

Study Start Date2020-06-26
Study Completion Date2026-06

Study Record Updates

Study Start Date2020-06-26
Study Completion Date2026-06

Terms related to this study

Keywords Provided by Researchers

  • Fuchs
  • Pseudophakic Bullous Keratopathy
  • Optical Coherence Tomography (OCT)
  • PBK

Additional Relevant MeSH Terms

  • Fuchs Dystrophy
  • Pseudophakic Bullous Keratopathy