OCT in Fuchs' Dystrophy

Description

This is an observational study using optical coherence tomography (OCT) technology to quantify corneal edema in Fuchs' endothelial dystrophy and predict refractive shift from resolving corneal edema after surgical treatments.

Conditions

Fuchs Dystrophy, Pseudophakic Bullous Keratopathy

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Study Overview

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Study Details

Study overview

This is an observational study using optical coherence tomography (OCT) technology to quantify corneal edema in Fuchs' endothelial dystrophy and predict refractive shift from resolving corneal edema after surgical treatments.

Evaluating Corneal Edema in Fuchs' Endothelial Dystrophy Using Optical Coherence Tomography

OCT in Fuchs' Dystrophy

Condition
Fuchs Dystrophy
Intervention / Treatment

-

Contacts and Locations

Portland

Oregon Health & Science University, Portland, Oregon, United States, 97239

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

For general information about clinical research, read Learn About Studies.

Eligibility Criteria

  • * Damaged or diseased corneal endothelium from Fuchs' or PBK
  • * Willingness to commit to required study visits
  • * Prior Endothelial Keratoplasty (EK) or any other surgery except uncomplicated cataract surgery
  • * Presence of a condition that increases the probability for treatment failure (e.g., heavily vascularized cornea, uncontrolled uveitis)
  • * Other primary endothelial dysfunction conditions (e.g., posterior polymorphous corneal dystrophy and congenital hereditary corneal dystrophy, iridocorneal endothelial syndrome)
  • * Central sub-epithelial or stromal scarring that could impact post-operative clarity assessment
  • * Peripheral anterior synechiae in the angle greater than 3 clock hours
  • * Hypotony
  • * Uncontrolled glaucoma
  • * Visually significant optic nerve or macular pathology

Ages Eligible for Study

18 Years to

Sexes Eligible for Study

ALL

Accepts Healthy Volunteers

No

Collaborators and Investigators

Oregon Health and Science University,

Winston Chamberlain, MD, PhD, PRINCIPAL_INVESTIGATOR, Oregon Health and Science University

Study Record Dates

2026-06