RECRUITING

Neutrophil Phenotypic Profiling and Acute Lung Injury in Patients After Cardiopulmonary Bypass (CPB)

Study Overview

This clinical trial focuses on testing the efficacy of different digital interventions to promote re-engagement in cancer-related long-term follow-up care for adolescent and young adult (AYA) survivors of childhood cancer.

Description

Acute lung injury (ALI) following cardiopulmonary bypass (CPB) is a serious complication, often prolonging the length of stay in ICU and potentially dealing to mortality. The objective of this study is to assess the mechanism of CPB-mediated acute lung injury in pediatric patients.

Official Title

Neutrophil Phenotypic Profiling and Acute Lung Injury in Patients After Cardiopulmonary Bypass (CPB)

Quick Facts

Study Start:2022-10-14
Study Completion:2026-12
Study Type:Not specified
Phase:Not Applicable
Enrollment:Not specified
Status:RECRUITING

Study ID

NCT04296071

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Ages Eligible for Study:Not specified to 12 Months
Sexes Eligible for Study:ALL
Accepts Healthy Volunteers:No
Standard Ages:CHILD
Inclusion CriteriaExclusion Criteria
  1. * Are \< 12months of age
  2. * Scheduled for cardiac surgical needing CPB
  3. * Preoperative SpO2 \> 90%
  1. * Lack of parental (or legal guardian's) consent
  2. * Preoperative SpO2 \< 90%
  3. * Preoperative oxygen therapy

Contacts and Locations

Study Contact

Sophia Koutsogiannaki, PhD
CONTACT
617-919-4725
sophia.koutsogiannaki@childrens.harvard.edu
Koichi Yuki, MD
CONTACT
617-355-6225
koichi.yuki@childrens.harvard.edu

Study Locations (Sites)

Boston Children's Hospital
Boston, Massachusetts, 02115
United States

Collaborators and Investigators

Sponsor: Sophia Koutsogiannaki

Study Record Dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Registration Dates

Study Start Date2022-10-14
Study Completion Date2026-12

Study Record Updates

Study Start Date2022-10-14
Study Completion Date2026-12

Terms related to this study

Additional Relevant MeSH Terms

  • Lung Injury
  • Cardiopulmonary Bypass