ACTIVE_NOT_RECRUITING

Preeclampsia Postpartum Antihypertensive Treatment

Study Overview

This clinical trial focuses on testing the efficacy of different digital interventions to promote re-engagement in cancer-related long-term follow-up care for adolescent and young adult (AYA) survivors of childhood cancer.

Description

The goal of this study is to compare whether antihypertensive treatment in the postpartum period decreases postpartum hypertension and its associated maternal morbidity, including risk of readmission and healthcare utilization in comparison with no treatment. Women with preeclampsia diagnosed during the antepartum, intrapartum or postpartum period will be randomized to either initiate antihypertensive treatment or standard of care. We hypothesize that postpartum antihypertensive treatment of patients with preeclampsia will decrease risk of hospital readmission, healthcare utilization and the number of severe range blood pressures at postpartum follow-up visits.

Official Title

Randomized Controlled Trial for Postpartum Antihypertensive Treatment of Women With Preeclampsia

Quick Facts

Study Start:2020-07-17
Study Completion:2025-06-30
Study Type:Not specified
Phase:Not Applicable
Enrollment:Not specified
Status:ACTIVE_NOT_RECRUITING

Study ID

NCT04298034

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Ages Eligible for Study:18 Years
Sexes Eligible for Study:FEMALE
Accepts Healthy Volunteers:No
Standard Ages:ADULT, OLDER_ADULT
Inclusion CriteriaExclusion Criteria
  1. * Age \>= 18 years old
  2. * Immediately postpartum (delivered in previous 96 hours)
  3. * Diagnosed with preeclampsia during pregnancy, labor or immediately postpartum
  4. * \>30% of blood pressures in the postpartum period were elevated (systolic 140 or higher OR diastolic 90 or higher)
  1. * Chronic hypertension with superimposed preeclampsia
  2. * Diagnosis of preeclampsia after discharge from delivery hospitalization
  3. * Persistent severe range blood pressures after delivery requiring initiation of antihypertensive regimen by the care team
  4. * \>50% of blood pressures in the postpartum period were normal (systolic less than 140 AND diastolic less than 90)

Contacts and Locations

Study Locations (Sites)

Medical College of Wisconsin-Froedtert Hospital
Milwaukee, Wisconsin, 53226
United States

Collaborators and Investigators

Sponsor: Medical College of Wisconsin

Study Record Dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Registration Dates

Study Start Date2020-07-17
Study Completion Date2025-06-30

Study Record Updates

Study Start Date2020-07-17
Study Completion Date2025-06-30

Terms related to this study

Additional Relevant MeSH Terms

  • Preeclampsia
  • Hypertension in Pregnancy