Brown Adipose Tissue Activation by Spinal Cord Stimulation

Description

The objective of this study is to investigate and utilize spinal cord stimulation (SCS) as an effective approach to eliciting weight loss and potentially alleviating Type 2 diabetes mellitus (DM), as evidenced by increasing metabolism of adipose tissue.

Conditions

Pain, Back, Obesity, Morbid, Type 2 Diabetes

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Study Overview

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Study Details

Study overview

The objective of this study is to investigate and utilize spinal cord stimulation (SCS) as an effective approach to eliciting weight loss and potentially alleviating Type 2 diabetes mellitus (DM), as evidenced by increasing metabolism of adipose tissue.

Brown Adipose Tissue Activation by Spinal Cord Stimulation

Brown Adipose Tissue Activation by Spinal Cord Stimulation

Condition
Pain, Back
Intervention / Treatment

-

Contacts and Locations

Portland

Oregon Health & Science University, Portland, Oregon, United States, 97239

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

For general information about clinical research, read Learn About Studies.

Eligibility Criteria

  • 1. Age: 21-70 years
  • 2. Persistent neuropathic leg and back pain
  • 3. Subjects who are already planning to undergo SCS for pain
  • 4. Subjects who have not received a prior SCS trial for pain
  • 5. Subjects with a BMI of 25-45, using formula; weight (lb) / \[height (in)\]2 x 703
  • 1. Not considering SCS for pain
  • 2. Forensic patient
  • 3. Taking beta blockers
  • 4. Weight change \> 5% within last 3 months
  • 5. Habitual tobacco use
  • 6. Habitual excessive alcohol use
  • 7. Pregnancy
  • 8. Decisionally impaired adults
  • 9. Children
  • 10. Neonates
  • 11. Subjects with a BMI of \<25 or \>45

Ages Eligible for Study

21 Years to 70 Years

Sexes Eligible for Study

ALL

Accepts Healthy Volunteers

No

Collaborators and Investigators

Oregon Health and Science University,

Kim Burchiel, MD, PRINCIPAL_INVESTIGATOR, Oregon Health and Science University

Study Record Dates

2026-10