RECRUITING

Characterization of the Nrf2 Response in Patients With Autosomal Dominant Polycystic Kidney Disease (ADPKD)

Study Overview

This clinical trial focuses on testing the efficacy of different digital interventions to promote re-engagement in cancer-related long-term follow-up care for adolescent and young adult (AYA) survivors of childhood cancer.

Description

The purpose of this study is to characterize oxidative stress and the Nrf2 antioxidant response in early stages of Autosomal Dominant Polycystic Kidney Disease (ADPKD), while identifying candidate biomarkers.

Official Title

Characterization of the Nrf2 Response in Patients With Autosomal Dominant Polycystic Kidney Disease (ADPKD)

Quick Facts

Study Start:2019-10-04
Study Completion:2025-05
Study Type:Not specified
Phase:Not Applicable
Enrollment:Not specified
Status:RECRUITING

Study ID

NCT04344769

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Ages Eligible for Study:18 Years to 30 Years
Sexes Eligible for Study:ALL
Accepts Healthy Volunteers:Yes
Standard Ages:ADULT
Inclusion CriteriaExclusion Criteria
  1. Age 18 years or older
  2. Willing and able to provide informed consent
  3. Able to understand and follow study procedures
  4. Stable medical condition
  1. Pregnancy or breastfeeding
  2. Severe psychiatric disorders
  3. Active substance abuse
  4. Unstable medical conditions
  5. Inability to comply with study requirements

Contacts and Locations

Study Contact

Ahmed Abdelfattah
CONTACT
Abdelfattah.Ahmed@mayo.edu
Maria V Irazabal, M.D., Ph.D
CONTACT
507-884-5628
irazabalmira.maria@mayo.edu

Principal Investigator

Maria V. Irazabal, M.D., Ph.D
PRINCIPAL_INVESTIGATOR
Mayo Translational PKD Center, Mayo Clinic

Study Locations (Sites)

Mayo Clinic in Rochester
Rochester, Minnesota, 55905
United States

Collaborators and Investigators

Sponsor: Mayo Clinic

  • Maria V. Irazabal, M.D., Ph.D, PRINCIPAL_INVESTIGATOR, Mayo Translational PKD Center, Mayo Clinic

Study Record Dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Registration Dates

Study Start Date2019-10-04
Study Completion Date2025-05

Study Record Updates

Study Start Date2019-10-04
Study Completion Date2025-05

Terms related to this study

Keywords Provided by Researchers

  • Oxidative Stress
  • Antioxidant Response
  • Nrf2
  • ADPKD

Additional Relevant MeSH Terms

  • Autosomal Dominant Polycystic Kidney Disease