CONFIRM: Magnetic Resonance Guided Radiation Therapy

Description

This research is being done to determine the safety and feasibility of using a type of radiation guided by magnetic resonance imaging (MRI) and chemotherapy to treat patients with gastric and breast cancer. The name of the radiation machine involved in this study is the MRIdian Linear Accelerator.

Conditions

Gastric Cancer, Invasive Breast Cancer, in Situ Breast Cancer, Mantle Cell Lymphoma, Larynx Cancer, Bladder Cancer

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Study Overview

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Study Details

Study overview

This research is being done to determine the safety and feasibility of using a type of radiation guided by magnetic resonance imaging (MRI) and chemotherapy to treat patients with gastric and breast cancer. The name of the radiation machine involved in this study is the MRIdian Linear Accelerator.

Clinical Onboard Utilization of Image Guided Radiation Therapy With Magnetic Resonance (CONFIRM): A Master Protocol

CONFIRM: Magnetic Resonance Guided Radiation Therapy

Condition
Gastric Cancer
Intervention / Treatment

-

Contacts and Locations

Boston

Brigham & Women's Hospital, Boston, Massachusetts, United States, 02115

Boston

Dana Farber Cancer Institute, Boston, Massachusetts, United States, 02115

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

For general information about clinical research, read Learn About Studies.

Eligibility Criteria

  • * Participants must have histologically or cytologically confirmed malignancy requiring radiation
  • * Age 18 years of older
  • * ECOG performance status ≤2 (Karnofsky ≥60%, see Appendix A)
  • * Ability to understand and the willingness to sign a written informed consent document.
  • * Any further criteria listed in the specific disease site cohort
  • * History of allergic reactions attributed to gadolinium-based IV contrast
  • * Severe claustrophobia or anxiety
  • * Participants who cannot undergo an MRI
  • * Any other exclusion criteria listed in the specific disease site cohort

Ages Eligible for Study

18 Years to

Sexes Eligible for Study

ALL

Accepts Healthy Volunteers

No

Collaborators and Investigators

Dana-Farber Cancer Institute,

Raymond Mak, MD, PRINCIPAL_INVESTIGATOR, Dana-Farber Cancer Institute

Study Record Dates

2029-06-18