CBD-Microglia PET Study

Description

This study aims to examine the effect of cannabidiol (CBD) pre-treatment on brain microglial activation in healthy human subjects. Secondarily, this study aims to examine the effect of cannabidiol (CBD) pre-treatment on central pain-sensitization in healthy human subjects.

Conditions

CBD, Healthy

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Study Overview

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Study Details

Study overview

This study aims to examine the effect of cannabidiol (CBD) pre-treatment on brain microglial activation in healthy human subjects. Secondarily, this study aims to examine the effect of cannabidiol (CBD) pre-treatment on central pain-sensitization in healthy human subjects.

Effect of Cannabidiol on Microglial Activation and Central Pain-Sensitization

CBD-Microglia PET Study

Condition
CBD
Intervention / Treatment

-

Contacts and Locations

New Haven

Connecticut Mental Health Center, New Haven, Connecticut, United States, 06519

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

For general information about clinical research, read Learn About Studies.

Eligibility Criteria

  • 1. Men and women aged 18- 55 years
  • 2. No significant medical or neurological illness
  • 3. No implanted metal devices that may pose a risk during MRI scanning
  • 4. Within the annual permissible radiation exposure
  • 5. Able to provide written informed consent.
  • 1. Current use of any medications
  • 2. Presence of metal in the body
  • 3. Pregnancy or lactation

Ages Eligible for Study

18 Years to 55 Years

Sexes Eligible for Study

ALL

Accepts Healthy Volunteers

Yes

Collaborators and Investigators

Yale University,

Rajiv Radhakrishnan, MD, PRINCIPAL_INVESTIGATOR, Yale University

Study Record Dates

2025-09-30