Fermented Food-Supplemented Diet in Ulcerative Colitis

Description

The purpose of this study is to see how a diet that supplements fermented foods effects inflammation and quality of life in patients with mild to moderate Ulcerative Colitis (UC). There is a paucity of research and an enormous need for better understanding of diet and intestinal inflammation. Fermented food have been shown to positively influence inflammatory cytokines and intestinal microbial diversity in healthy volunteers.

Conditions

Inflammatory Bowel Diseases, Diet Modification, Ulcerative Colitis

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Study Overview

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Study Details

Study overview

The purpose of this study is to see how a diet that supplements fermented foods effects inflammation and quality of life in patients with mild to moderate Ulcerative Colitis (UC). There is a paucity of research and an enormous need for better understanding of diet and intestinal inflammation. Fermented food have been shown to positively influence inflammatory cytokines and intestinal microbial diversity in healthy volunteers.

Effects of a Fermented Food-Supplemented on Patients with Ulcerative Colitis

Fermented Food-Supplemented Diet in Ulcerative Colitis

Condition
Inflammatory Bowel Diseases
Intervention / Treatment

-

Contacts and Locations

Palo Alto

Stanford University, Palo Alto, California, United States, 94305

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

For general information about clinical research, read Learn About Studies.

Eligibility Criteria

  • * Written informed consent
  • * Male or female subjects, ≥18 years of age
  • * Confirmed diagnosis of UC
  • * Symptomatic disease defined as partial Mayo Score 2 to 7 (inclusive)
  • * Elevated fecal calprotectin
  • * Women who are pregnant, nursing or expect to be pregnant
  • * Intolerance to fermented food
  • * Individuals with a body mass index (BMI) lower than 18
  • * Individuals diagnosed with a serious medical condition (unless approved in writing by a physician)
  • * Individuals who have been severely weakened by a disease or medical procedure
  • * Individuals with more than mild-moderate cardiovascular disease or life-threatening cancer (as determined by patient's physician) unless approved by a physician
  • * Individuals with history of severe cardiac disease (particularly uncompensated congestive heart failure NYHA grade 2 or more or LVEF \< 40%)
  • * History of relevant intestinal surgery such as total or hemi-colectomy, proctocolectomy, stoma.

Ages Eligible for Study

18 Years to

Sexes Eligible for Study

ALL

Accepts Healthy Volunteers

No

Collaborators and Investigators

Stanford University,

Sidhartha Sinha, MD, PRINCIPAL_INVESTIGATOR, Stanford University

Study Record Dates

2027-06