VENOUS: A Translational Study of Enterococcal Bacteremia

Description

The purpose of this study is to assemble a multicenter prospective cohort of patients with enterococcal bloodstream infections (BSIs) to provide data on outcomes of patients with enterococcal BSIs for sample size calculations for future trials, as well as to characterize enterococcal isolates causing BSIs in order to comprehensively dissect the molecular epidemiology of infecting organisms for future studies.

Conditions

Enterococcal Bacteremia

Study Overview

Study Details

Study overview

The purpose of this study is to assemble a multicenter prospective cohort of patients with enterococcal bloodstream infections (BSIs) to provide data on outcomes of patients with enterococcal BSIs for sample size calculations for future trials, as well as to characterize enterococcal isolates causing BSIs in order to comprehensively dissect the molecular epidemiology of infecting organisms for future studies.

VENOUS: A Translational Study of Enterococcal Bacteremia

VENOUS: A Translational Study of Enterococcal Bacteremia

Condition
Enterococcal Bacteremia
Intervention / Treatment

-

Contacts and Locations

Miami

Jackson Health System, University of Miami Miller School of Medicine, Miami, Florida, United States, 33136

Detroit

Henry Ford Hospital and Medical Centers, Detroit, Michigan, United States, 48202

Jackson

University of Mississippi Medical Center, Jackson, Mississippi, United States, 39216

Chapel Hill

University of North Carolina, Chapel Hill, North Carolina, United States, 27599

Pittsburgh

University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, United States, 15213

Houston

MD Anderson Cancer Center, Houston, Texas, United States, 77030

Houston

The University of Texas Health Science Center at Houston, Houston, Texas, United States, 77030

Seattle

Fred Hutchinson Cancer Research Center, Seattle, Washington, United States, 98109

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

For general information about clinical research, read Learn About Studies.

Eligibility Criteria

  • * Hospitalized patient
  • * ≥1 positive blood culture with Enterococcus spp. (VRE or VSE) during hospitalization
  • * bacterial isolate(s) is/are available for further characterization
  • * Repeat blood culture(s) within 7 days from the first positive culture
  • * Cultures obtained from patients not admitted to the hospital
  • * Isolate(s) not available for further studies.

Ages Eligible for Study

18 Years to

Sexes Eligible for Study

ALL

Accepts Healthy Volunteers

No

Collaborators and Investigators

The University of Texas Health Science Center, Houston,

Cesar A. Arias, MD, MSc, PhD, PRINCIPAL_INVESTIGATOR, The University of Texas Health Science Center, Houston

Study Record Dates

2025-08-31