Targeted TDCS to Enhance Speech-Language Treatment Outcome in Persons With Chronic Post-Stroke Aphasia.

Description

62 patients who are one year post stroke and have Aphasia as a result of that stroke will be recruited. Participants will have 4 assessment sessions and 15 treatment sessions. The TDCS will be to right Inferior Frontal Gyrus (IFG) (25 active, 25 sham) for 15 days. A combined semantic feature analysis/phonological components analysis treatment will be paired with the stimulation. Two assessment sessions will be pretreatment, 1 session immediately post-treatment, and 1 session at 3 months follow-up.

Conditions

Stroke, Aphasia

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Study Overview

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Study Details

Study overview

62 patients who are one year post stroke and have Aphasia as a result of that stroke will be recruited. Participants will have 4 assessment sessions and 15 treatment sessions. The TDCS will be to right Inferior Frontal Gyrus (IFG) (25 active, 25 sham) for 15 days. A combined semantic feature analysis/phonological components analysis treatment will be paired with the stimulation. Two assessment sessions will be pretreatment, 1 session immediately post-treatment, and 1 session at 3 months follow-up.

Targeted Transcranial Direct Current Stimulation to Enhance Speech-Language Treatment Outcome in Persons With Chronic Post-Stroke Aphasia

Targeted TDCS to Enhance Speech-Language Treatment Outcome in Persons With Chronic Post-Stroke Aphasia.

Condition
Stroke
Intervention / Treatment

-

Contacts and Locations

Albuquerque

University of New Mexico Center for Brain Recovery and Repair, Albuquerque, New Mexico, United States, 87106

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

For general information about clinical research, read Learn About Studies.

Eligibility Criteria

  • 1. aged 25-85
  • 2. must be greater than 1 year post-stroke
  • 3. must have a diagnosis of aphasia based on impaired performance on the Western Aphasia Battery-Revised, Boston Naming Test, or during discourse production
  • 4. must be left-hemisphere dominant as demonstrated by aphasia onset subsequent to left hemisphere damage
  • 5. must be stimulable for naming
  • 1. comorbid neurological disease.
  • 2. damage to the anterior right hemisphere.
  • 3. significant mood disorder.
  • 4. substance/alcohol dependence or abuse within the past year
  • 5. presence of any implanted electrical device or contraindications to tDCS or MRI
  • 6. recent medical instability (within 4 weeks)
  • 7. pregnancy

Ages Eligible for Study

25 Years to 85 Years

Sexes Eligible for Study

ALL

Accepts Healthy Volunteers

No

Collaborators and Investigators

University of New Mexico,

Jessica Richardson, Ph.D., PRINCIPAL_INVESTIGATOR, University of New Mexico

Study Record Dates

2026-04-30