RECRUITING

Mechanisms and Modulation of Pain Modulatory Capacity

Study Overview

This clinical trial focuses on testing the efficacy of different digital interventions to promote re-engagement in cancer-related long-term follow-up care for adolescent and young adult (AYA) survivors of childhood cancer.

Description

This project proposes to understand the sources of pain variability, and demonstrate that pain variability represents fluctuation in natural pain management. The project further proposes to determine if endogenous capacity to modulate pain can be trained to maximize their body's ability to manage pain, much as the way in which athletic performance can be trained.

Official Title

Mechanisms and Modulation of Pain Modulatory Capacity

Quick Facts

Study Start:2020-11-30
Study Completion:2025-05-01
Study Type:Not specified
Phase:Not Applicable
Enrollment:Not specified
Status:RECRUITING

Study ID

NCT04441619

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Ages Eligible for Study:18 Years to 70 Years
Sexes Eligible for Study:ALL
Accepts Healthy Volunteers:Yes
Standard Ages:ADULT, OLDER_ADULT
Inclusion CriteriaExclusion Criteria
  1. * Asymptomatic people (ie no current pain conditions)
  2. * Participants with widespread muscle pain (WMP) aged 18 years of age and older
  3. * Participants with WMP must meet the ACR (2010) diagnostic criteria of multiple regions of muscle pain
  4. * The asymptomatic group will be free of current wrist/hand, elbow, or shoulder pain and chronic pain conditions (eg irritable bowel syndrome, FM)
  1. 1. Participation in a conditioning program specific to the biceps in the past 6 months
  2. 2. Any report of wrist/hand, elbow, or shoulder pain in the last 3 months
  3. 3. Any chronic medical conditions that may affect pain perception (e.g., diabetes, high blood pressure), kidney dysfunction, muscle damage, or major psychiatric disorder
  4. 4. Use of any intervention (including but not limited to medication, massage, and stretching) for symptoms induced by pain training for the duration of the study
  5. 5. Positive result on pre-MRI metal screening or pregnancy test due to contraindication for the MRI environment.
  6. 6. Any participant with ferromagnetic metal in the head, neck, or abdominal cavity

Contacts and Locations

Study Contact

Mark D Bishop, PhD
CONTACT
352-2736112
bish@ufl.edu
Jeff Boissoneault, PhD
CONTACT
352-2736147
jboissoneault@phhp.ufl.edu

Principal Investigator

Michael E Robinson, PhD
PRINCIPAL_INVESTIGATOR
University of Florida

Study Locations (Sites)

Unversity of Florida
Gainesville, Florida, 32611
United States

Collaborators and Investigators

Sponsor: University of Florida

  • Michael E Robinson, PhD, PRINCIPAL_INVESTIGATOR, University of Florida

Study Record Dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Registration Dates

Study Start Date2020-11-30
Study Completion Date2025-05-01

Study Record Updates

Study Start Date2020-11-30
Study Completion Date2025-05-01

Terms related to this study

Additional Relevant MeSH Terms

  • Musculoskeletal Pain