RECRUITING

Impact of Sinus Surgery on Individuals With Cystic Fibrosis

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Conditions

Chronic Rhinosinusitis (Diagnosis)Cystic FibrosisChronic RhinosinusitisEndoscopic Sinus Surgery

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Study Overview

This clinical trial focuses on testing the efficacy of different digital interventions to promote re-engagement in cancer-related long-term follow-up care for adolescent and young adult (AYA) survivors of childhood cancer.

Description

This study will be a prospective, observational study of patients who undergo endoscopic sinus surgery for cystic fibrosis-related chronic rhinosinusitis (CRS). Individuals who do not undergo surgery but are treated medically for CRS will also be enrolled to serve as a control group. Outcomes analyzed will include pulmonary, quality of life, and others.

Official Title

The Impact of Sinus Surgery in the Era of Highly Effective Modulatory Therapy

Quick Facts

Study Start:2020-07-01
Study Completion:2025-01-31
Study Type:Not specified
Phase:Not Applicable
Enrollment:Not specified
Status:RECRUITING

Study ID

NCT04469439

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Ages Eligible for Study:18 Years to 99 Years
Sexes Eligible for Study:ALL
Accepts Healthy Volunteers:No
Standard Ages:ADULT, OLDER_ADULT
Inclusion CriteriaExclusion Criteria
  1. 1. Subjects between the ages of 18 years old (inclusive) and 99 years old (inclusive, subjects over the age of 89 will be recorded to be 89 years old).
  2. 2. Diagnosed with cystic fibrosis as established by genetic testing combined with clinical assessment and/or sweat chloride
  3. 3. Diagnosed with chronic rhinosinusitis by multidisciplinary sinusitis guidelines
  4. 4. chronic rhinosinusitis symptoms persisting beyond initial medical treatment
  5. 5. Counseled for endoscopic sinus surgery and ongoing medical therapy with each patient electing their preferred treatment
  1. 1. Underwent endoscopic sinus surgery in past 12 months
  2. 2. Will obtain follow up care at non-participating institutions
  3. 3. Unable to complete follow-up surveys

Contacts and Locations

Study Contact

Daniel M Beswick, MD
CONTACT
310-206-8457
dbeswick@mednet.ucla.edu
Rhea Churi, BS
CONTACT
310-923-2534
rchuri@mednet.ucla.edu

Principal Investigator

Daniel M Beswick, MD
PRINCIPAL_INVESTIGATOR
University of California, Los Angeles

Study Locations (Sites)

University of California, Los Angeles
Los Angeles, California, 90095
United States
Stanford University
Stanford, California, 94305
United States
University of Colorado
Aurora, Colorado, 80045
United States
National Jewish Health
Denver, Colorado, 80206
United States
University of North Carolina
Chapel Hill, North Carolina, 27514
United States
Oregon Health Science University
Portland, Oregon, 97239
United States
Medical University of South Carolina
Charleston, South Carolina, 29425
United States
Vanderbilt University Medical Center
Nashville, Tennessee, 37232
United States
University of Utah
Salt Lake City, Utah, 84132
United States

Collaborators and Investigators

Sponsor: University of California, Los Angeles

  • Daniel M Beswick, MD, PRINCIPAL_INVESTIGATOR, University of California, Los Angeles

Study Record Dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Registration Dates

Study Start Date2020-07-01
Study Completion Date2025-01-31

Study Record Updates

Study Start Date2020-07-01
Study Completion Date2025-01-31

Terms related to this study

Keywords Provided by Researchers

  • Chronic Rhinosinusitis
  • Cystic Fibrosis
  • Endoscopic Sinus Surgery

Additional Relevant MeSH Terms

  • Chronic Rhinosinusitis (Diagnosis)
  • Cystic Fibrosis