RECRUITING

Comparison of the Q-NRG+ Indirect Calorimetry Device Versus the V(Max) Encore Device in Mechanically Ventilated Children

Study Overview

This clinical trial focuses on testing the efficacy of different digital interventions to promote re-engagement in cancer-related long-term follow-up care for adolescent and young adult (AYA) survivors of childhood cancer.

Description

The overarching aim of this proposal is to examine the feasibility of the Q-NRG+ indirect calorimetry device and its agreement with (Vmax) Encore indirect calorimetry device in mechanically ventilated children. The overall hypothesis of this study is that the Q-NRG+ will provide minute-to-minute oxygen consumption (VO2) and carbon dioxide production (CO2) measurements that are in agreement with those obtained by the standard indirect calorimetry device currently used at our institution (Vmax Encore).

Official Title

Comparison of the Q-NRG+ Indirect Calorimetry Device Versus the V(Max) Encore Device in Mechanically Ventilated Children

Quick Facts

Study Start:2020-01-01
Study Completion:2024-12-31
Study Type:Not specified
Phase:Not Applicable
Enrollment:Not specified
Status:RECRUITING

Study ID

NCT04482556

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Ages Eligible for Study:10 Years to 18 Years
Sexes Eligible for Study:ALL
Accepts Healthy Volunteers:No
Standard Ages:CHILD, ADULT
Inclusion CriteriaExclusion Criteria
  1. * Children mechanically ventilated with endotracheal tube of tracheostomy in standard ventilatory modes such as SIMV-PC, SIMV-VC or PRVC
  2. * Age \> 10 years AND weight \> 10kg
  3. * FIO2 \< 60%
  4. * PEEP \< 8
  5. * ETT leak \< 10%
  6. * The attending physician of record plans to order indirect calorimetry and considers research activity safe
  1. * Hemodynamic instability (hypotension according to PALS/ACLS formula or requiring 2 or greater vasoactive infusions)
  2. * Presence of chest tubes with ongoing air leak
  3. * Patients requiring ECMO support
  4. * Patients undergoing end-of-life care
  5. * Primary provider declines enrollment.

Contacts and Locations

Study Contact

Ben D Albert, MD
CONTACT
617-355-7327
ben.albert@childrens.harvard.edu
Nilesh M Mehta, MD
CONTACT
617-355-7327
Nilesh.Mehta@childrens.harvard.edu

Principal Investigator

Nilesh M Mehta, MD
STUDY_DIRECTOR
Boston Children's Hospital

Study Locations (Sites)

Boston Children's Hospital
Boston, Massachusetts, 02115
United States

Collaborators and Investigators

Sponsor: Boston Children's Hospital

  • Nilesh M Mehta, MD, STUDY_DIRECTOR, Boston Children's Hospital

Study Record Dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Registration Dates

Study Start Date2020-01-01
Study Completion Date2024-12-31

Study Record Updates

Study Start Date2020-01-01
Study Completion Date2024-12-31

Terms related to this study

Keywords Provided by Researchers

  • Pediatrics
  • Indirect Calorimetry
  • Enteral Nutrition
  • Metabolism
  • Critical Care

Additional Relevant MeSH Terms

  • Calorimetry, Indirect
  • Oxygen Consumption
  • Metabolism
  • Mechanical Ventilation