Study on the Compensatory Mechanism of Iodine Nutrition and the Optimal Intake Level of Lactating Women

Description

Due to the lack of direct evidence of optimal iodine intake of Chinese children, pregnant and lactating women and infants were found during the recent revision of Chinese dietary reference intakes (DRIs) of iodine in 2013 by the applicant Pro. Zhang, and no systematical research about compensatory mechanism of iodine nutrition in lactating women was found yet. Previous study funded by United Nations International Children's Emergency Fund (UNICEF) cooperated with the international experts on iodine and key project of national natural science foundation of China under the guidance of Pro. Zhang, had obtained the safe intake range of iodine from children and pregnant women, more than 10 joint papers were published, which laid the foundation of population study and international cooperation.

Conditions

Nutritional Requirements

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Study Overview

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Study Details

Study overview

Due to the lack of direct evidence of optimal iodine intake of Chinese children, pregnant and lactating women and infants were found during the recent revision of Chinese dietary reference intakes (DRIs) of iodine in 2013 by the applicant Pro. Zhang, and no systematical research about compensatory mechanism of iodine nutrition in lactating women was found yet. Previous study funded by United Nations International Children's Emergency Fund (UNICEF) cooperated with the international experts on iodine and key project of national natural science foundation of China under the guidance of Pro. Zhang, had obtained the safe intake range of iodine from children and pregnant women, more than 10 joint papers were published, which laid the foundation of population study and international cooperation.

Study on the Compensatory Mechanism of Iodine Nutrition and the Optimal Intake Level of Lactating Women

Study on the Compensatory Mechanism of Iodine Nutrition and the Optimal Intake Level of Lactating Women

Condition
Nutritional Requirements
Intervention / Treatment

-

Contacts and Locations

Boston

Boston University School of Medicine; Iodine Global Network (IGN), Boston, Massachusetts, United States, 02101-02117

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

For general information about clinical research, read Learn About Studies.

Eligibility Criteria

  • * Women in their third trimester:⑴Aged 18-40, who have lived in the area for 1 year;⑵Single pregnancy;⑶Those who have no special dietary habits;
  • * Lactating woman:⑴Breastfeeding a child;⑵Normal thyroid function during pregnancy;⑶Term delivery (38-42 weeks of gestation);
  • * Infants and young children:⑴0-6 months;⑵Breastfeeding;⑶Full term (38-42 weeks of gestation);⑷Normal birth weight (2500-4000g);⑸The thyroid-stimulating hormone (TSH) value of heel blood was normal;⑹Apgar score 8.
  • * Women in their third trimester:⑴Smoking or drinking;⑵Iodized drugs or contrast agents have been used in the past year;⑶A history of thyroid disease, autoimmune disease, endocrine disease, heart disease, chronic disease or family hereditary disease, etc;
  • * Lactating woman:⑴A history of thyroid disease, autoimmune disease, endocrine disease, heart disease, chronic disease or family hereditary disease, etc;
  • * Infants and young children:⑴Have pathological jaundice, autoimmune disease, congenital heart disease and other diseases.

Ages Eligible for Study

1 Day to 40 Years

Sexes Eligible for Study

ALL

Accepts Healthy Volunteers

Yes

Collaborators and Investigators

Tianjin Medical University,

JianQiang Lai, PRINCIPAL_INVESTIGATOR, Institute of Nutrition and Health, Chinese Center for Disease Control and Prevention

XueSong Wang, PRINCIPAL_INVESTIGATOR, Shandong Institute of Endemic Disease Control and Prevention

YiFan Duan, PRINCIPAL_INVESTIGATOR, Institute of Nutrition and Health, Chinese Center for Disease Control and Prevention

GuiJun Tan, PRINCIPAL_INVESTIGATOR, Tianjin Medical University

Wen Chen, PRINCIPAL_INVESTIGATOR, Tianjin Medical University

YanTing Chen, PRINCIPAL_INVESTIGATOR, Tianjin Medical University

Min Gao, PRINCIPAL_INVESTIGATOR, Tianjin Medical University

ZiYun Pan, PRINCIPAL_INVESTIGATOR, Tianjin Medical University

Michael B Zimmermann, doctorate, STUDY_CHAIR, Swiss federal institute of Technology (ETH)

Elizabeth N Pearce, doctorate, STUDY_CHAIR, Boston University School of Medicine; Iodine Global Network (IGN)

Maria Andersson, doctorate, STUDY_CHAIR, Swiss federal institute of Technology (ETH); Iodine Global Network (IGN)

Study Record Dates

2024-12-31