The Use of Indocyanine Green as a Diagnostic Adjunct for Pediatric Solid Malignancies

Description

Use of indocyanine green will augment the accuracy of identification and resection of both primary solid malignancies as well as their pulmonary metastases, where applicable We will conduct a prospective feasibility study of pediatric patients with solid malignancies with or without lung metastatases who present at the time of initial diagnosis or relapse. These patients will receive a targeted dye to aid in the resection of these metastases. We plan to assess ICG as it relates to: 1. Diagnostic accuracy using pathologic correlation as gold standard measure 2. Short and long term event free and overall survival

Conditions

Metastatic Disease, Primary Tumor, Solid Malignancies

Study Overview

Study Details

Study overview

Use of indocyanine green will augment the accuracy of identification and resection of both primary solid malignancies as well as their pulmonary metastases, where applicable We will conduct a prospective feasibility study of pediatric patients with solid malignancies with or without lung metastatases who present at the time of initial diagnosis or relapse. These patients will receive a targeted dye to aid in the resection of these metastases. We plan to assess ICG as it relates to: 1. Diagnostic accuracy using pathologic correlation as gold standard measure 2. Short and long term event free and overall survival

The Use of Indocyanine Green as a Diagnostic Adjunct for Pediatric Solid

The Use of Indocyanine Green as a Diagnostic Adjunct for Pediatric Solid Malignancies

Condition
Metastatic Disease
Intervention / Treatment

-

Contacts and Locations

Cincinnati

Cincinnati Childrens Hospital Medical Center, Cincinnati, Ohio, United States, 45229

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

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Eligibility Criteria

  • 1. Clinical evaluation and physical exam
  • 2. Radiologic study including ultrasound, CT scan, and/or MRI
  • 3. Pathologic diagnosis after biopsy
  • 1. Those patients and parents/guardians unwilling to provide consent/assent.
  • 2. Pregnant and/or women who are breast feeding.
  • 3. Patients with Iodine allergies

Ages Eligible for Study

1 Day to 45 Years

Sexes Eligible for Study

ALL

Accepts Healthy Volunteers

No

Collaborators and Investigators

Roshni Dasgupta,

Study Record Dates

2025-06