International Spontaneous Coronary Artery Dissection (SCAD) "iSCAD" Registry

Description

The aim of "iSCAD," the International Spontaneous Coronary Artery Dissection (SCAD) Registry, is to serve as an internationally collaborative, multicenter registry coordinated by an experienced and centralized coordinating center in an effort to increase the pace of participant recruitment, and thereby increase statistical power of studies related to SCAD. The ultimate goal of iSCAD Registry is to facilitate the development of best practices and clinical guidelines for preventing SCAD or its recurrence. This observational study will be prospective and retrospective in its recruitment and will collect clinical information to better understand the natural history and prognosis for SCAD.

Conditions

Spontaneous Coronary Artery Dissection

Study Overview

Study Details

Study overview

The aim of "iSCAD," the International Spontaneous Coronary Artery Dissection (SCAD) Registry, is to serve as an internationally collaborative, multicenter registry coordinated by an experienced and centralized coordinating center in an effort to increase the pace of participant recruitment, and thereby increase statistical power of studies related to SCAD. The ultimate goal of iSCAD Registry is to facilitate the development of best practices and clinical guidelines for preventing SCAD or its recurrence. This observational study will be prospective and retrospective in its recruitment and will collect clinical information to better understand the natural history and prognosis for SCAD.

The International Spontaneous Coronary Artery Dissection "iSCAD" Registry (SCAD)

International Spontaneous Coronary Artery Dissection (SCAD) "iSCAD" Registry

Condition
Spontaneous Coronary Artery Dissection
Intervention / Treatment

-

Contacts and Locations

Los Angeles

Cedars Sinai, Los Angeles, California, United States, 90048

Los Angeles

UCLA (University of California, Los Angeles), Los Angeles, California, United States, 93003

San Francisco

Kaiser Permanente Northern California, San Francisco, California, United States, 94115

Aurora

University of Colorado, Aurora, Colorado, United States, 80045

Hartford

Hartford Hospital, Hartford, Connecticut, United States, 06106

Tampa

University of South Florida, Tampa, Florida, United States, 33602

Atlanta

Emory Healthcare System, Atlanta, Georgia, United States, 30308

Chicago

Northwestern Medicine, Chicago, Illinois, United States, 60611

Lexington

University of Kentucky, Lexington, Kentucky, United States, 40508

Baltimore

Johns Hopkins, Baltimore, Maryland, United States, 21224

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

For general information about clinical research, read Learn About Studies.

Eligibility Criteria

  • 1. Inpatient wards of the enrolling medical centers during the acute presentation of SCAD, or
  • 2. Outpatient cardiovascular clinics of enrolling medical centers.
  • * 18 years of age or older
  • * Diagnosis of SCAD or history of SCAD based on coronary angiography, either catheter-based or coronary CTA
  • * Suspected SCAD by coronary angiography
  • 1. Coronary dissection in association with atherosclerosis or as a result of iatrogenic injury
  • 2. Inability to provide informed consent
  • 3. Inability to complete study-related patient questionnaires
  • 4. Inability to understand and complete patient questionnaires independently

Ages Eligible for Study

18 Years to

Sexes Eligible for Study

ALL

Accepts Healthy Volunteers

No

Collaborators and Investigators

SCAD Alliance,

Esther Kim, MD, STUDY_CHAIR, Chair, Steering Committee

Malissa Wood, MD, PRINCIPAL_INVESTIGATOR, Member, Steering Committee

Sahar Naderi, MD, PRINCIPAL_INVESTIGATOR, Member, Steering Committee

Study Record Dates

2025-12-31