RECRUITING

Motor Skill Acquisition Between Individuals With Neurological Disorders and Healthy Individuals

Study Overview

This clinical trial focuses on testing the efficacy of different digital interventions to promote re-engagement in cancer-related long-term follow-up care for adolescent and young adult (AYA) survivors of childhood cancer.

Description

Stroke survivors frequently show persistent gait deficits in their chronic stages even after years of intensive rehabilitation. This may be caused by diminished capability of re-acquiring motor skills post stroke. Thus, the overall purpose of this research project is to examine stroke survivors' capability of learning a novel leg task over 3 visits, 1-2 weeks apart. The capability of learning a new skill is then correlated with the individual's neurological functions (nerve activity and movement coordination) and her/his gait performance (gait speed, gait symmetry, and force production).

Official Title

Comparison of Motor Skill Acquisition Between Individuals With Neurological Disorders

Quick Facts

Study Start:2013-04-04
Study Completion:2024-12-31
Study Type:Not specified
Phase:Not Applicable
Enrollment:Not specified
Status:RECRUITING

Study ID

NCT04503187

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Ages Eligible for Study:21 Years to 90 Years
Sexes Eligible for Study:ALL
Accepts Healthy Volunteers:Not specified
Standard Ages:ADULT, OLDER_ADULT
Inclusion CriteriaExclusion Criteria
  1. * Healthy adults have no ongoing neurological, musculoskeletal issues.
  2. * Individuals with chronic stroke had medical history of a unilateral stroke occurring ≥ 6 months prior to enrollment.
  3. * Individuals have multiple sclerosis disease diagnosed by his/her physician
  4. * MRI or CT evidence from the imaging report shown that the stroke and multiple sclerosis disease primarily involve cortical and subcortical regions.
  5. * Individuals with chronic stroke have hemiparesis involving the lower extremity.
  6. * Individuals with chronic stroke or multiple sclerosis have no passive range of motion limitation in bilateral hips and knees. Limitation of ankle passive range of motion to 10 degrees of dorsiflexion or less.
  7. * Visual acuity can be corrected by glasses or contact lens to 20/20.
  8. * Able to walk independently with/without assistant devices for 10 meters.
  9. * Able to maintain standing position without any assistance for more than 30 sec.
  10. * Evaluation of cognitive status: Mini-mental status examination (MMSE) score ≥ 24.
  1. * Pregnant women.
  2. * MRI or CT evidence of involvement of the basal ganglia or cerebellum, or evidence of any other brain damage or malignant neoplasm or tumors.
  3. * Have any metal implants, cardiac pacemakers, or history of seizures.
  4. * Ongoing orthopedic or other neuromuscular disorders that will restrict exercise training.
  5. * Any vestibular dysfunction or unstable angina.
  6. * Significant cognitive deficits (inability to follow a 2-step command) or severe receptive or global aphasia\*

Contacts and Locations

Study Contact

Shih-Chiao Tseng, PT, PhD
CONTACT
713-794-2309
stseng@twu.edu

Principal Investigator

Shih-Chiao Tseng, PT, PhD
PRINCIPAL_INVESTIGATOR
Texas Woman's University School of Physical Therapy

Study Locations (Sites)

Texas Woman's University
Houston, Texas, 77030
United States

Collaborators and Investigators

Sponsor: Texas Woman's University

  • Shih-Chiao Tseng, PT, PhD, PRINCIPAL_INVESTIGATOR, Texas Woman's University School of Physical Therapy

Study Record Dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Registration Dates

Study Start Date2013-04-04
Study Completion Date2024-12-31

Study Record Updates

Study Start Date2013-04-04
Study Completion Date2024-12-31

Terms related to this study

Additional Relevant MeSH Terms

  • Stroke
  • Multiple Sclerosis