Effect of Thickened Feeds on Swallow Physiology in Children With Dysphagia

Description

This study will examine the effects of varying liquid viscosity on swallow physiology in infants with oropharyngeal dysphagia and brief resolved unexplained event (BRUE) and other children with dysphagia that would be at risk for symptoms of swallow dysfunction.

Conditions

Dysphagia, Aspiration, Brief Resolved Unexplained Event (BRUE), Apparent Life Threatening Event (ALTE)

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Study Overview

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Study Details

Study overview

This study will examine the effects of varying liquid viscosity on swallow physiology in infants with oropharyngeal dysphagia and brief resolved unexplained event (BRUE) and other children with dysphagia that would be at risk for symptoms of swallow dysfunction.

Effect of Thickened Feeds on Swallow Physiology in Children With Dysphagia

Effect of Thickened Feeds on Swallow Physiology in Children With Dysphagia

Condition
Dysphagia
Intervention / Treatment

-

Contacts and Locations

Boston

Boston Children's Hospital, Boston, Massachusetts, United States, 02115

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

For general information about clinical research, read Learn About Studies.

Eligibility Criteria

  • * Age 0 to 21 years
  • * Admitted to Boston Children's Hospital after experiencing first lifetime BRUE, or with dysphagia symptoms such that they would be at risk for BRUE or other symptoms of swallowing difficulty
  • * Have had videofluoroscopic swallow study performed or might have future videofluoroscopic swallow study performed.
  • * Any pre-existing medical diagnoses that exclude brief resolved unexplained event diagnosis including seizure disorders and cyanotic congenital heart disease
  • * Any nasal/pharyngeal/esophageal anomalies that might affect safe placement of the pharyngeal motility catheter
  • * Children fed exclusively by enteral tube
  • * Allergy to rice cereal or Gelmix thickener, which will be used to adjust liquid viscosity

Ages Eligible for Study

to 21 Years

Sexes Eligible for Study

ALL

Accepts Healthy Volunteers

No

Collaborators and Investigators

Boston Children's Hospital,

Daniel R Duncan, MD, MPH, PRINCIPAL_INVESTIGATOR, Boston Children's Hospital

Rachel Rosen, MD, MPH, STUDY_DIRECTOR, Boston Children's Hospital

Sudarshan Jadcherla, MD, STUDY_DIRECTOR, Nationwide Children's Hospital

Taher Omari, PhD, STUDY_DIRECTOR, Flinders University

Samuel Nurko, MD, MPH, STUDY_DIRECTOR, Boston Children's Hospital

Study Record Dates

2025-08-31