Financial Toxicity and Quality of Life in Patients With TGCT

Description

This is a cross-sectional, observational study employing validated questionnaires to investigate financial toxicity in subjects with testicular germ cell tumors (TGCT). As background, TGCTs are the most common malignancies among men from age 15-35. Treatment is highly curative, but often consists of intensive multi-cycle chemotherapy with significant potential for physical toxicity. The treatment course itself is disruptive and long term physical and mental health consequences can increase risk for financial toxicity. Thus, we aim to study financial toxicity in both patients with TGCT actively receiving treatment and in TGCT survivors. There will be two separate cohorts: Cohort 1 will consist of subjects with recently diagnosed TGCT who will undergo multi-agent, multi-cycle chemotherapy and Cohort 2 will consist of subjects who have completed chemotherapy and are long-term survivors.

Conditions

Testicular Neoplasm

Study Overview

Study Details

Study overview

This is a cross-sectional, observational study employing validated questionnaires to investigate financial toxicity in subjects with testicular germ cell tumors (TGCT). As background, TGCTs are the most common malignancies among men from age 15-35. Treatment is highly curative, but often consists of intensive multi-cycle chemotherapy with significant potential for physical toxicity. The treatment course itself is disruptive and long term physical and mental health consequences can increase risk for financial toxicity. Thus, we aim to study financial toxicity in both patients with TGCT actively receiving treatment and in TGCT survivors. There will be two separate cohorts: Cohort 1 will consist of subjects with recently diagnosed TGCT who will undergo multi-agent, multi-cycle chemotherapy and Cohort 2 will consist of subjects who have completed chemotherapy and are long-term survivors.

Financial Toxicity and Quality of Life in Patients With Testicular Germ Cell Tumors

Financial Toxicity and Quality of Life in Patients With TGCT

Condition
Testicular Neoplasm
Intervention / Treatment

-

Contacts and Locations

San Antonio

Mays Cancer Center, San Antonio, Texas, United States, 78229

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

For general information about clinical research, read Learn About Studies.

Eligibility Criteria

  • * Recently diagnosed TGCT
  • * Patients with histologically or clinically confirmed germ cell tumor.
  • * Age \> 18 years of age.
  • * Anticipated treatment with multicycle (\> 2 cycles) / multiagent chemotherapy
  • * Within 4 weeks of starting C1D1 chemotherapy
  • * Signed informed consent
  • * Long-term survivors
  • * Age \> 18 years of age
  • * Patients with histologically or clinically confirmed germ cell tumor.
  • * Completed treatment for germ cell tumor with multicycle (\> 2 cycles) / multiagent chemotherapy.
  • * Within years 1-5 of surveillance since Day 1 of last cycle of chemotherapy
  • * Signed informed consent
  • * Recently diagnosed TGCT
  • * Patients planned to receive \<2 cycles of chemotherapy
  • * Starting chemotherapy greater than 4 weeks after signing consent and completing initial survey.
  • * Starting chemotherapy prior to consenting and completing initial survey.
  • * Long-term survivors
  • * Patients undergoing active chemotherapy
  • * Patients who did not complete 1st line chemotherapy.

Ages Eligible for Study

18 Years to

Sexes Eligible for Study

MALE

Accepts Healthy Volunteers

No

Collaborators and Investigators

The University of Texas Health Science Center at San Antonio,

Deepak Pruthi, MD, PRINCIPAL_INVESTIGATOR, The University of Texas Health Science Center at San Antonio

Study Record Dates

2025-12