Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.
For general information about clinical research, read Learn About Studies.
Eligibility Criteria
- 1. Diagnosis of Autism Spectrum Disorder (ASD), Asperger's or Autism.
- 2. Meet criteria for ASD on clinical assessments (ADOS-2 or CARS/BOSA if conducted remotely \& ADI-R)
- 3. Aged between 12-45 years old
- 4. Have a reliable informant who can complete relevant questionnaires
- 5. Must have previously not responded or not tolerated 2 treatments.
- 1. Any contraindications for TMS e.g. history of seizures
- 2. Pregnancy
- 3. Any current or past history of any physical condition which in the investigator's opinion might put the subject at risk or interfere with study results interpretation.
- 4. Active substance use (\<1 week) or intoxication verified by toxicology screen--of cocaine, amphetamines, benzodiazepines
- 5. Showing symptoms of withdrawal from alcohol or benzodiazepines
- 6. DSM-5 diagnosis of bipolar disorder or a psychotic disorder e.g. schizophrenia.
- 7. Significant sensory impairments such as blindness or deafness.
- 8. Any other indication the PI feels would comprise data
- 9. Current severe insomnia (must sleep a minimum of 4 hours the night before stimulation)
- 10. IQ\<50 or not testable using IQ measures and no historical IQ score available
- 11. Currently taking Clozapine or another medication that the PI determines increases the risk of TMS or may disrupt the efficacy.
- 12. A motor threshold that is too high to allow safe/tolerable treatment.
Ages Eligible for Study
12 Years to 45 Years
Sexes Eligible for Study
ALL
Accepts Healthy Volunteers
No