Jump: MR Simulation For Radiation Therapy Master Protocol

Description

This is a master protocol for a prospective Phase I-II study evaluating feasibility and efficacy of incorporating magnetic resonance imaging (MRI) simulation into the planning of radiation treatments.

Conditions

Prostate Cancer, Recurrent Adenocarcinoma, Liver Cancer, Head and Neck Cancer

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Study Overview

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Study Details

Study overview

This is a master protocol for a prospective Phase I-II study evaluating feasibility and efficacy of incorporating magnetic resonance imaging (MRI) simulation into the planning of radiation treatments.

Judging MR Simulation Procedures: A Phase I-II Study of the Use of Magnetic Resonance Imaging Simulation in the Planning of Radiation Treatments

Jump: MR Simulation For Radiation Therapy Master Protocol

Condition
Prostate Cancer
Intervention / Treatment

-

Contacts and Locations

Boston

Brigham and Women Hospital, Boston, Massachusetts, United States, 02115

Boston

Dana Farber Cancer Institute, Boston, Massachusetts, United States, 02215

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

For general information about clinical research, read Learn About Studies.

Eligibility Criteria

  • * Participants must have a confirmed malignancy requiring radiation therapy.
  • * Age: 18 years or older
  • * ECOG performance status ≤2 (Karnofsky ≥60%, see Appendix A)
  • * Ability to understand and the willingness to sign a written informed consent document.
  • * Disease-specific eligibility criteria will be specified in the appropriate subprotocol.
  • * For MRI involving contrast, history of allergic reactions attributed to gadolinium based IV contrast. Note: If patient will not receive contrast, this is not applicable
  • * Participants who cannot undergo an MRI
  • * Disease-specific exclusion criteria will be specified in the appropriate subprotocol

Ages Eligible for Study

18 Years to

Sexes Eligible for Study

ALL

Accepts Healthy Volunteers

No

Collaborators and Investigators

Dana-Farber Cancer Institute,

Raymond Mak, MD, PRINCIPAL_INVESTIGATOR, Brigham and Women's Hospital

Study Record Dates

2026-10-22