RECRUITING

Sleep Spindles and Memory in Rolandic Epilepsy

Study Overview

This clinical trial focuses on testing the efficacy of different digital interventions to promote re-engagement in cancer-related long-term follow-up care for adolescent and young adult (AYA) survivors of childhood cancer.

Description

The investigators are recruiting children with Rolandic epilepsy and children without epilepsy (aged 4 years old and above) for a non-invasive brain imaging study using Magnetic Resonance Imaging (MRI), Magnetoencephalography/Electroencephalography (MEG/EEG), and experimental tasks. The investigators hope to determine the brain circuits and brain rhythms affected in these children and ultimately identify new treatment options for childhood epilepsy patients.

Official Title

Auditory Stimulation Effect on Spindles and Sleep Dependent Learning in Rolandic Epilepsy

Quick Facts

Study Start:2021-01-16
Study Completion:2025-12-31
Study Type:Not specified
Phase:Not Applicable
Enrollment:Not specified
Status:RECRUITING

Study ID

NCT04569708

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Ages Eligible for Study:4 Years to 18 Years
Sexes Eligible for Study:ALL
Accepts Healthy Volunteers:Yes
Standard Ages:CHILD, ADULT
Inclusion CriteriaExclusion Criteria
  1. 1. Ages 4-18 years
  2. 2. Diagnosed with childhood epilepsy with centrotemporal spikes (CECTS) or Rolandic epilepsy by child neurologist
  3. 3. Has EEG with sleep activated centrotemporal spikes
  4. 4. Has had at least 1 focal motor or generalized seizure
  1. 1. Has abnormal brain MRI
  2. 2. Has other unrelated neurological disease
  3. 3. Unable to have an MRI/MEG
  4. 1. Claustrophobic
  5. 2. History of frequent vomiting
  6. 3. Permanent metal in body, braces
  7. 4. Over MRI weight limit: 350lbs

Contacts and Locations

Study Contact

Catherine Chu, MD
CONTACT
617-726-6540
cjchu@mgh.harvard.edu
Erin Berja, BS
CONTACT
631-317-0413
eberja@mgh.harvard.edu

Principal Investigator

Catherine Chu, MD
PRINCIPAL_INVESTIGATOR
Massachusetts General Hospital

Study Locations (Sites)

Athinoula A. Martinos Center Biomedical Imaging
Charlestown, Massachusetts, 02129
United States

Collaborators and Investigators

Sponsor: Massachusetts General Hospital

  • Catherine Chu, MD, PRINCIPAL_INVESTIGATOR, Massachusetts General Hospital

Study Record Dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Registration Dates

Study Start Date2021-01-16
Study Completion Date2025-12-31

Study Record Updates

Study Start Date2021-01-16
Study Completion Date2025-12-31

Terms related to this study

Additional Relevant MeSH Terms

  • Rolandic Epilepsy
  • Rolandic Epilepsy, Benign
  • Centrotemporal Epilepsy
  • Centrotemporal; EEG Spikes, Epilepsy of Childhood
  • Epilepsy; Seizure
  • Epilepsy