Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.
For general information about clinical research, read Learn About Studies.
Eligibility Criteria
- * Inclusion Criteria
- * Boys or girls
- * Ages 8-10 years
- * All races
- * All ethnicities
- * Children who were determined to have normal weight (BMI \<85th percentile) already determined under Mitochondria (MI) Energy (IRB Protocol: 260376)
- * Participants willing to stop taking nutritional supplements (e.g., multivitamins, vitamin D, fish oil, probiotics, prebiotics, immune boosters, and others) for at least 2 weeks prior to each study testing visit
- * Children without an infection requiring antibiotics willing to be rescheduled after at least 2 months of finalizing antibiotic treatment.
- * Children without viral infections such as diarrhea, cold, or flu willing to be rescheduled after at least 2 weeks of resolution of symptoms.
- * Children determined sedentary or active, based on both peak oxygen uptake (VO2) and accelerometer data, as described below: Children who completed a peak fitness test during MI Energy (IRB Protocol: 260376), and for whom peak VO2 data are as follows:
- * 89 ≤ 80 ≥115 ≥105 FFMI, fat-free mass index
- * Children who completed Dual-energy x-ray absorptiometry (DXA) measures during MI Energy study (IRB Protocol: 260376)
- * Children whose parents consented to the following in the MI Energy study (IRB Protocol: 260376): o A) be contacted about future follow-up studies to MI Energy, and having the data that is collected about their child in MI Energy being used also in these follow-up studies; and
- * B) information collected in the MI Energy study may be used in future research related to bioenergetics (for example, blood cell mitochondria function), nutrition, obesity, cardiovascular health, or development; and
- * C) any biological samples collected in the MI Energy study may be used in future research related to bioenergetics (for example, blood cell mitochondria function), nutrition, obesity, cardiovascular health, or development.
- * • Participants who have been excluded from participation in the study MI Energy (IRB Protocol: 260376)
- * Participants whose parents report any change in medical history that may potentially affect participation and/or study outcomes as determined by PI
- * Weight loss \>3 kg in last 6 months
- * Taking medications that knowingly influences protein metabolism
- * Phenylketonuria
Ages Eligible for Study
8 Years to 10 Years
Sexes Eligible for Study
ALL
Accepts Healthy Volunteers
Yes