Effects of Blocking Blue Light at Night Post CABG, AVR, MVR, CABG AVR, CABG MVR, or SAH

Description

Purpose The purpose of this study is to determine whether filtering out blue light at nighttime reduces post-surgical inflammation and/or moderates cognitive decline and mood and sleep alterations in patients undergoing elective CABG, AVR, MVR, CABG AVR, CABG MVR, or SAH surgery. If manipulating nighttime light in hospital rooms improves patient outcomes, then it would be a relatively easy and inexpensive innovation that could reduce post-surgical complications and save millions of dollars per year in health care costs by shortening the length of hospital stays and reducing morbidity. The investigators aim to determine the relationship between inflammation and cognitive dysfunction after cardiac surgery.

Conditions

Circadian Rhythm Disorders

Talk to us

Study Overview

On this page

Study Details

Study overview

Purpose The purpose of this study is to determine whether filtering out blue light at nighttime reduces post-surgical inflammation and/or moderates cognitive decline and mood and sleep alterations in patients undergoing elective CABG, AVR, MVR, CABG AVR, CABG MVR, or SAH surgery. If manipulating nighttime light in hospital rooms improves patient outcomes, then it would be a relatively easy and inexpensive innovation that could reduce post-surgical complications and save millions of dollars per year in health care costs by shortening the length of hospital stays and reducing morbidity. The investigators aim to determine the relationship between inflammation and cognitive dysfunction after cardiac surgery.

Effects of Blocking Blue Light at Night on Patient Outcomes After Elective CABG, AVR, MVR, CABG AVR, CABG MVR, or SAH

Effects of Blocking Blue Light at Night Post CABG, AVR, MVR, CABG AVR, CABG MVR, or SAH

Condition
Circadian Rhythm Disorders
Intervention / Treatment

-

Contacts and Locations

Morgantown

West Virginia University Heart and Vascular Institute, Morgantown, West Virginia, United States, 26506

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

For general information about clinical research, read Learn About Studies.

Eligibility Criteria

  • * Both men and women that are undergoing elective (non-emergency)
  • * on-pump CABG surgery,
  • * AVR,
  • * MVR,
  • * CABG AVR,
  • * CABG MVR or
  • * SAH
  • * No history of diagnosed psychiatric disorders or organ failure
  • * Evidence or diagnosis of dementia or other cognitive deficit
  • * Diagnosed psychiatric disorder (including depression and anxiety)
  • * Organ failure \[kidney (creatine \> 1.5 mg/dL), liver, etc.\]
  • * Chronic obstructive pulmonary disease,
  • * Any immune disorder
  • * Acute infection
  • * Prior cardiac surgery
  • * Elective aneurysms
  • * Combined cardiac operations
  • * Left main stenosis greater than 70%
  • * Left ventricular ejection fraction (LVEF) lower than 0.5
  • * Any condition that increases likelihood of the need for a blood transfusion during or after the surgery
  • * Clotting disorder
  • * Suspected less than 8th grade English reading comprehension level

Ages Eligible for Study

45 Years to 75 Years

Sexes Eligible for Study

ALL

Accepts Healthy Volunteers

No

Collaborators and Investigators

West Virginia University,

Randy J Nelson, PhD, PRINCIPAL_INVESTIGATOR, West Virginia University

Study Record Dates

2025-03