Theta Burst Stimulation Plus Habit Override Training for Compulsive Behaviors

Description

This project seeks to identify causal neural mechanisms underlying unwanted, repetitive behaviors (compulsions). Using non-invasive brain stimulation coupled with practice in a computer task, we will modulate activity in a target brain region and measure effects on compulsive behaviors and related measures. This work could ultimately lead to the ability to treat compulsions more effectively by targeting the regions of the brain that can help or hinder attempts to overcome compulsions.

Conditions

Compulsive Behavior, Obsessive-Compulsive Disorder

Study Overview

Study Details

Study overview

This project seeks to identify causal neural mechanisms underlying unwanted, repetitive behaviors (compulsions). Using non-invasive brain stimulation coupled with practice in a computer task, we will modulate activity in a target brain region and measure effects on compulsive behaviors and related measures. This work could ultimately lead to the ability to treat compulsions more effectively by targeting the regions of the brain that can help or hinder attempts to overcome compulsions.

Experimental Manipulation of OFC Function and Behavioral Context: Towards an Integrative Translational Model of Compulsive Behaviors

Theta Burst Stimulation Plus Habit Override Training for Compulsive Behaviors

Condition
Compulsive Behavior
Intervention / Treatment

-

Contacts and Locations

Pittsburgh

Western Psychiatric Institute and Clinic, Pittsburgh, Pennsylvania, United States, 15213

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

For general information about clinical research, read Learn About Studies.

Eligibility Criteria

  • 1. Be between the ages of 18 and 60 years
  • 2. Endorse problematic compulsive behaviors, per self-report and clinician-administered measures.
  • 3. Agree to video taping of structured clinical interview
  • 4. Report that they will reside in the Pittsburgh area for at least 5 weeks
  • 1. Failure to meet standard MRI

Ages Eligible for Study

18 Years to 60 Years

Sexes Eligible for Study

ALL

Accepts Healthy Volunteers

No

Collaborators and Investigators

Rebecca Price,

Rebecca B Price, PhD, PRINCIPAL_INVESTIGATOR, University of Pittsburgh

Study Record Dates

2027-01-02