COMPLETED

Theta Burst Stimulation Plus Habit Override Training for Compulsive Behaviors

Study Overview

This clinical trial focuses on testing the efficacy of different digital interventions to promote re-engagement in cancer-related long-term follow-up care for adolescent and young adult (AYA) survivors of childhood cancer.

Description

This project seeks to identify causal neural mechanisms underlying unwanted, repetitive behaviors (compulsions). Using non-invasive brain stimulation coupled with practice in a computer task, we will modulate activity in a target brain region and measure effects on compulsive behaviors and related measures. This work could ultimately lead to the ability to treat compulsions more effectively by targeting the regions of the brain that can help or hinder attempts to overcome compulsions.

Official Title

Experimental Manipulation of OFC Function and Behavioral Context: Towards an Integrative Translational Model of Compulsive Behaviors

Quick Facts

Study Start:2020-12-28
Study Completion:2025-12-15
Study Type:Not specified
Phase:Not Applicable
Enrollment:Not specified
Status:COMPLETED

Study ID

NCT04580043

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Ages Eligible for Study:18 Years to 60 Years
Sexes Eligible for Study:ALL
Accepts Healthy Volunteers:No
Standard Ages:ADULT
Inclusion CriteriaExclusion Criteria
  1. 1. Be between the ages of 18 and 60 years
  2. 2. Endorse problematic compulsive behaviors, per self-report and clinician-administered measures.
  3. 3. Agree to video taping of structured clinical interview
  4. 4. Report that they will reside in the Pittsburgh area for at least 5 weeks
  1. 1. Failure to meet standard MRI

Contacts and Locations

Principal Investigator

Rebecca B Price, PhD
PRINCIPAL_INVESTIGATOR
University of Pittsburgh

Study Locations (Sites)

Western Psychiatric Institute and Clinic
Pittsburgh, Pennsylvania, 15213
United States

Collaborators and Investigators

Sponsor: Rebecca Price

  • Rebecca B Price, PhD, PRINCIPAL_INVESTIGATOR, University of Pittsburgh

Study Record Dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Registration Dates

Study Start Date2020-12-28
Study Completion Date2025-12-15

Study Record Updates

Study Start Date2020-12-28
Study Completion Date2025-12-15

Terms related to this study

Additional Relevant MeSH Terms

  • Compulsive Behavior
  • Obsessive-Compulsive Disorder