Cardiovascular and Neurovascular Regulation in GWI

Description

Brain blood flow regulation and autonomic dysfunction will be measured in Veterans with and without Gulf War Illness who served in the Gulf War between 1990 and 1992.

Conditions

Brain Blood Flow, Neurovascular Control

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Study Overview

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Study Details

Study overview

Brain blood flow regulation and autonomic dysfunction will be measured in Veterans with and without Gulf War Illness who served in the Gulf War between 1990 and 1992.

Autonomic Dysfunction, Brain Blood Flow and Cognitive Decline in Veterans With Gulf War Illness

Cardiovascular and Neurovascular Regulation in GWI

Condition
Brain Blood Flow
Intervention / Treatment

-

Contacts and Locations

Madison

University of Wisconsin-Madison, Madison, Wisconsin, United States, 53706

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

For general information about clinical research, read Learn About Studies.

Eligibility Criteria

  • * Deployed to the Persian Gulf between 1990-1992
  • * Body mass \<300 lbs
  • * Diagnosis of Gulf War Illness based on CMI/CDC and Kansas definitions or No diagnosis of Gulf War Illness
  • * Current or lifetime evidence of: Type II diabetes, neurological disease, cancer treatment, rheumatoid arthritis, lupus, bipolar disorder, psychotic disorders, or mood disorders with psychotic features
  • * Current illicit substance use or partial remission for less than 1 year
  • * Taking multiple sedatives or anticonvulsant medications
  • * Currently pregnant
  • * Absolute contraindications to exercise testing
  • * Contraindications to MRI
  • * Other significant medical conditions at investigator's discretion

Ages Eligible for Study

45 Years to 68 Years

Sexes Eligible for Study

ALL

Accepts Healthy Volunteers

Yes

Collaborators and Investigators

University of Wisconsin, Madison,

Jill N Barnes, PhD, PRINCIPAL_INVESTIGATOR, University of Wisconsin, Madison

Study Record Dates

2025-03