RECRUITING

Ketamine in Patients Undergoing TEVAR Procedures Receiving NCI

Study Overview

This clinical trial focuses on testing the efficacy of different digital interventions to promote re-engagement in cancer-related long-term follow-up care for adolescent and young adult (AYA) survivors of childhood cancer.

Description

The objective of this study is to identify the opioid-sparing effects, and pain-reduction potential of low dose, sub-dissociative ketamine on patients undergoing thoracic endovascular aortic repair (TEVAR) procedures receiving naloxone continuous infusion (NCI).

Official Title

A Randomized, Double-blind, Placebo-controlled, Study to Identify the Opioid-sparing Effects, and Pain-reduction Potential of Low Dose Ketamine on Patients Undergoing TEVAR Procedures Receiving NCI

Quick Facts

Study Start:2020-12-08
Study Completion:2027-08
Study Type:Not specified
Phase:Not Applicable
Enrollment:Not specified
Status:RECRUITING

Study ID

NCT04600089

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Ages Eligible for Study:18 Years to 90 Years
Sexes Eligible for Study:ALL
Accepts Healthy Volunteers:No
Standard Ages:ADULT, OLDER_ADULT
Inclusion CriteriaExclusion Criteria
  1. * willing to give informed consent
  2. * scheduled for elective thoracic aorta repair or thoracoabdominal aortic repair
  3. * requires naloxone continuous infusion for spinal prophylaxis
  1. * allergy to ketamine, acetaminophen, or fentanyl
  2. * diagnosis of schizophrenia
  3. * history of hydrocephalus or central nervous system mass
  4. * incarcerated individuals
  5. * pregnant or lactating individuals

Contacts and Locations

Study Contact

Eric Johnson, PharmD
CONTACT
8593235722
eric.johnson@uky.edu

Principal Investigator

Anna Rockich, Pharm D
STUDY_DIRECTOR
University of Kentucky
Samuel Tyagi, MD
PRINCIPAL_INVESTIGATOR
University of Kentucky

Study Locations (Sites)

University of Kentucky Medical Center
Lexington, Kentucky, 40536
United States

Collaborators and Investigators

Sponsor: Sam Tyagi

  • Anna Rockich, Pharm D, STUDY_DIRECTOR, University of Kentucky
  • Samuel Tyagi, MD, PRINCIPAL_INVESTIGATOR, University of Kentucky

Study Record Dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Registration Dates

Study Start Date2020-12-08
Study Completion Date2027-08

Study Record Updates

Study Start Date2020-12-08
Study Completion Date2027-08

Terms related to this study

Keywords Provided by Researchers

  • naloxone
  • ketamine
  • aortic repair
  • spinal cord ischemia

Additional Relevant MeSH Terms

  • Descending Aortic Dissection
  • Postoperative Pain
  • Thoracoabdominal Aortic Aneurysm