Registry for Intra-Operative Radiotherapy During Breast Conserving Surgery in Patients With Early Stage Breast Cancer

Description

This is a prospective, registry study that will enroll all women with early stage breast cancer who will be treated with intraoperative radiotherapy (IORT) during breast-conserving surgery. The purpose of this study is to further validate the long-term effectiveness and safety of this treatment method. We aim to assess short and long-term patient outcomes associated with IORT, including perioperative complications, local and distance disease recurrences, as well as disease-free survival and overall survival.

Conditions

Early-stage Breast Cancer, Breast Carcinoma in Situ, Breast Neoplasms

Study Overview

Study Details

Study overview

This is a prospective, registry study that will enroll all women with early stage breast cancer who will be treated with intraoperative radiotherapy (IORT) during breast-conserving surgery. The purpose of this study is to further validate the long-term effectiveness and safety of this treatment method. We aim to assess short and long-term patient outcomes associated with IORT, including perioperative complications, local and distance disease recurrences, as well as disease-free survival and overall survival.

Research Registry for Intra-Operative Radiotherapy (IORT) During Breast Conserving Surgery in Patients With in Situ and Early Stage Breast Cancer

Registry for Intra-Operative Radiotherapy During Breast Conserving Surgery in Patients With Early Stage Breast Cancer

Condition
Early-stage Breast Cancer
Intervention / Treatment

-

Contacts and Locations

Santa Monica

John Wayne Cancer Institute, Providence Saint John's Health Center, Santa Monica, California, United States, 90404

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

For general information about clinical research, read Learn About Studies.

Eligibility Criteria

  • * Clinical stage Tis, T1, or T2(≤ 3cm), N0, M0 (AJCC Classification)
  • * Unifocal Disease
  • * Candidate for breast-conserving surgery
  • * Recommended treatment by multidisciplinary team
  • * Clinical stage T3-4, N1-3, M1
  • * Multifocal disease

Ages Eligible for Study

18 Years to

Sexes Eligible for Study

ALL

Accepts Healthy Volunteers

No

Collaborators and Investigators

Saint John's Cancer Institute,

Janie Grumley, MD, PRINCIPAL_INVESTIGATOR, John Wayne Cancer Institute, Providence Saint John's Health Center

Study Record Dates

2028-10-03