RECRUITING

Evaluation of SUMMIT BRUSH in Treatment of Blepharitis

Conditions

Study Overview

This clinical trial focuses on testing the efficacy of different digital interventions to promote re-engagement in cancer-related long-term follow-up care for adolescent and young adult (AYA) survivors of childhood cancer.

Description

Dry Eye Disease (DED) is a multifactorial disease that affects \~15-30 million people in the USA alone. It creates an enormous societal and economic burden, decreases productivity in the workplace, and affects the quality of lives of the people affected by this disease. DED is primarily caused by blepharitis, a chronic inflammation of the eyelid margins. If left untreated, blepharitis results in the obstruction and loss of the glands responsible for tear film production. The standard of care is the use of self-administered at home commercially available products, e.g., eyelid foams, gels, and pads. Although these products are helpful, they have limitations. Patients often require expensive in office procedures, e.g., lid debridement with exfoliation devices or more expensive procedures. The scope of this project is to evaluate the effectiveness of a new self-administered disposable ocular brush used in conjunction with the most common eyelid cleanser. The investigators are looking to see if combining the microexfoliation provided by the brush with the eyelid cleanser is more effective at removing the eyelid debris than the cleanser alone.

Official Title

Evaluation of SUMMIT BRUSH in Treatment of Blepharitis

Quick Facts

Study Start:2020-07-21
Study Completion:2022-07-18
Study Type:Not specified
Phase:Not Applicable
Enrollment:Not specified
Status:RECRUITING

Study ID

NCT04603222

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Ages Eligible for Study:18 Years
Sexes Eligible for Study:ALL
Accepts Healthy Volunteers:Yes
Standard Ages:ADULT, OLDER_ADULT
Inclusion CriteriaExclusion Criteria
  1. * Clinical signs and symptoms of blepharitis (Staphylococcal and Demodex).
  2. * Must exhibit visible collarettes, clear sleeves, and scurfs on the eyelid margins upon Slit Lamp Biomicroscopy.
  1. * Hordeolum
  2. * Chalazion
  3. * Periorbital cellulitis
  4. * Allergic eyelid dermatitis.
  5. * Acute bacterial conjunctivitis
  6. * Open periorbital wounds.

Contacts and Locations

Study Contact

Giles E Duffield, Ph.D.
CONTACT
5746311834
duffield.2@nd.edu

Principal Investigator

Giles E Duffield, Ph.D.
PRINCIPAL_INVESTIGATOR
University of Notre Dame

Study Locations (Sites)

University of Colorado
Boulder, Colorado, 80303
United States
Michiana Eye Center
Mishawaka, Indiana, 46545
United States
Kentucky Eye Institute
Lexington, Kentucky, 40509
United States

Collaborators and Investigators

Sponsor: University of Notre Dame

  • Giles E Duffield, Ph.D., PRINCIPAL_INVESTIGATOR, University of Notre Dame

Study Record Dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Registration Dates

Study Start Date2020-07-21
Study Completion Date2022-07-18

Study Record Updates

Study Start Date2020-07-21
Study Completion Date2022-07-18

Terms related to this study

Additional Relevant MeSH Terms

  • Blepharitis