Evaluation of SUMMIT BRUSH in Treatment of Blepharitis

Description

Dry Eye Disease (DED) is a multifactorial disease that affects \~15-30 million people in the USA alone. It creates an enormous societal and economic burden, decreases productivity in the workplace, and affects the quality of lives of the people affected by this disease. DED is primarily caused by blepharitis, a chronic inflammation of the eyelid margins. If left untreated, blepharitis results in the obstruction and loss of the glands responsible for tear film production. The standard of care is the use of self-administered at home commercially available products, e.g., eyelid foams, gels, and pads. Although these products are helpful, they have limitations. Patients often require expensive in office procedures, e.g., lid debridement with exfoliation devices or more expensive procedures. The scope of this project is to evaluate the effectiveness of a new self-administered disposable ocular brush used in conjunction with the most common eyelid cleanser. The investigators are looking to see if combining the microexfoliation provided by the brush with the eyelid cleanser is more effective at removing the eyelid debris than the cleanser alone.

Conditions

Blepharitis

Study Overview

Study Details

Study overview

Dry Eye Disease (DED) is a multifactorial disease that affects \~15-30 million people in the USA alone. It creates an enormous societal and economic burden, decreases productivity in the workplace, and affects the quality of lives of the people affected by this disease. DED is primarily caused by blepharitis, a chronic inflammation of the eyelid margins. If left untreated, blepharitis results in the obstruction and loss of the glands responsible for tear film production. The standard of care is the use of self-administered at home commercially available products, e.g., eyelid foams, gels, and pads. Although these products are helpful, they have limitations. Patients often require expensive in office procedures, e.g., lid debridement with exfoliation devices or more expensive procedures. The scope of this project is to evaluate the effectiveness of a new self-administered disposable ocular brush used in conjunction with the most common eyelid cleanser. The investigators are looking to see if combining the microexfoliation provided by the brush with the eyelid cleanser is more effective at removing the eyelid debris than the cleanser alone.

Evaluation of SUMMIT BRUSH in Treatment of Blepharitis

Evaluation of SUMMIT BRUSH in Treatment of Blepharitis

Condition
Blepharitis
Intervention / Treatment

-

Contacts and Locations

Boulder

University of Colorado, Boulder, Colorado, United States, 80303

Mishawaka

Michiana Eye Center, Mishawaka, Indiana, United States, 46545

Lexington

Kentucky Eye Institute, Lexington, Kentucky, United States, 40509

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

For general information about clinical research, read Learn About Studies.

Eligibility Criteria

  • * Clinical signs and symptoms of blepharitis (Staphylococcal and Demodex).
  • * Must exhibit visible collarettes, clear sleeves, and scurfs on the eyelid margins upon Slit Lamp Biomicroscopy.
  • * Hordeolum
  • * Chalazion
  • * Periorbital cellulitis
  • * Allergic eyelid dermatitis.
  • * Acute bacterial conjunctivitis
  • * Open periorbital wounds.

Ages Eligible for Study

18 Years to

Sexes Eligible for Study

ALL

Accepts Healthy Volunteers

Yes

Collaborators and Investigators

University of Notre Dame,

Giles E Duffield, Ph.D., PRINCIPAL_INVESTIGATOR, University of Notre Dame

Study Record Dates

2022-07-18