Lung Cancer Risk and Early Detection in Firefighters

Description

This study will evaluate whether LDCT findings differ between firefighters and non-fighters, the relationship between occupational exposures and LDCT findings, and whether a proteomics assay can further risk-stratify screen-detected nodules among a study population of 850 current and retired firefighters and 1,120 matched controls.

Conditions

Lung Cancer, Lung Diseases

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Study Overview

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Study Details

Study overview

This study will evaluate whether LDCT findings differ between firefighters and non-fighters, the relationship between occupational exposures and LDCT findings, and whether a proteomics assay can further risk-stratify screen-detected nodules among a study population of 850 current and retired firefighters and 1,120 matched controls.

Lung Cancer Risk and Early Detection in Firefighters

Lung Cancer Risk and Early Detection in Firefighters

Condition
Lung Cancer
Intervention / Treatment

-

Contacts and Locations

Boston

Massachusetts General Hospital, Boston, Massachusetts, United States, 02114

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

For general information about clinical research, read Learn About Studies.

Eligibility Criteria

  • * 40-80 years of age or with 10 years of firefighting experience
  • * Current or retired firefighters
  • * No personal history of lung cancer
  • * Willing and able to receive LDCT screening at MGH or who have been screened via LDCT within the past year at MGH or another institution, and are willing to release their images to the study
  • * Any active cancer (undergoing treatment or diagnosed within the past 5 years)

Ages Eligible for Study

40 Years to 80 Years

Sexes Eligible for Study

ALL

Accepts Healthy Volunteers

Yes

Collaborators and Investigators

Massachusetts General Hospital,

Erica T Warner, ScD, PRINCIPAL_INVESTIGATOR, Massachusetts General Hospital

Lecia V Sequist, MD, PRINCIPAL_INVESTIGATOR, Massachusetts General Hospital

Study Record Dates

2024-06-30