The Utility and Feasibility of Mt-sDNA as a Surveillance Procedure in Colorectal Cancer Survivors

Description

The purpose of this research study is to determine whether testing of stool for a panel of markers will enable us to detect polyps and cancer compared to standard testing.

Conditions

Adenocarcinoma of the Colon, Adenocarcinoma of the Rectum, Stage I Colorectal Cancer, Stage II Colorectal Cancer, Stage III Colorectal Cancer

Talk to us

Study Overview

On this page

Study Details

Study overview

The purpose of this research study is to determine whether testing of stool for a panel of markers will enable us to detect polyps and cancer compared to standard testing.

The Utility and Feasibility of Mt-sDNA as a Surveillance Procedure in Colorectal Cancer Survivors

The Utility and Feasibility of Mt-sDNA as a Surveillance Procedure in Colorectal Cancer Survivors

Condition
Adenocarcinoma of the Colon
Intervention / Treatment

-

Contacts and Locations

Cleveland

University Hospitals Seidman Cancer Center, Case Comprehensive Cancer Center, Cleveland, Ohio, United States, 44106

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

For general information about clinical research, read Learn About Studies.

Eligibility Criteria

  • * Diagnosis of stage I, II or III adenocarcinoma of the colon or rectum
  • * Receipt of preoperative colonoscopy
  • * Receipt of bowel resection; use of adjuvant chemotherapy or radiation therapy as clinically indicated
  • * Stage IV colorectal cancer
  • * Surgical treatment with subtotal colectomy or total proctocolectomy
  • * Diagnosis of inflammatory bowel disease (ulcerative colitis or Crohn's disease)
  • * Diagnosis of polyposis syndrome including Lynch syndrome or familial polyposis
  • * Presence of advanced adenomas (1 cm or larger, villous features and/or high grade dysplasia) that were not removed at the preoperative colonoscopy or contained in the resection specimen.
  • * Inability to provide informed consent
  • * Inability to understand spoken and written English
  • * Medical comorbidities that would be contraindications to sedation or that would preclude any benefit of routine surveillance post-resection. These would be at the discretion of the participant's providers.

Ages Eligible for Study

18 Years to

Sexes Eligible for Study

ALL

Accepts Healthy Volunteers

No

Collaborators and Investigators

Case Comprehensive Cancer Center,

Gregory Cooper, MD, PRINCIPAL_INVESTIGATOR, University Hospitals Cleveland Medical Center, Case Comprehensive Cancer Center

Study Record Dates

2025-06-30