Tobacco Treatment Optimization and Preferences During Concurrent Cancer Treatment

Description

Smoking cessation has been shown to improve the effectiveness and reduce the morbidity of tobacco-related cancer treatments. We will identify effective smoking cessation strategies for patients who are receiving treatment for tobacco-related cancer. In this trial, patients' preferences in smoking cessation therapy will be the principal determinant by providers in developing a three component regimen of pharmaceutical therapy, counseling, and nicotine replacement therapy. This study will identify this cohort's preferences for smoking cessation strategies. We will then examine the impact of utilizing patient preferences upon cessation efficacy by directly comparing cessation success in this study with our recently completed study of the same population using the same tobacco treatments which were randomly assigned.

Conditions

Smoking Cessation, Cancer, Treatment-Related

Study Overview

Study Details

Study overview

Smoking cessation has been shown to improve the effectiveness and reduce the morbidity of tobacco-related cancer treatments. We will identify effective smoking cessation strategies for patients who are receiving treatment for tobacco-related cancer. In this trial, patients' preferences in smoking cessation therapy will be the principal determinant by providers in developing a three component regimen of pharmaceutical therapy, counseling, and nicotine replacement therapy. This study will identify this cohort's preferences for smoking cessation strategies. We will then examine the impact of utilizing patient preferences upon cessation efficacy by directly comparing cessation success in this study with our recently completed study of the same population using the same tobacco treatments which were randomly assigned.

Tobacco Treatment Optimization and Preferences During Concurrent Cancer Treatment

Tobacco Treatment Optimization and Preferences During Concurrent Cancer Treatment

Condition
Smoking Cessation
Intervention / Treatment

-

Contacts and Locations

Ashland

Kings Daughters Medical Center - Ashland, Ashland, Kentucky, United States, 41101

Bowling Green

Med Center Health, Bowling Green, Kentucky, United States, 42101

Lexington

University Of Kentucky, Markey Cancer Center, Lexington, Kentucky, United States, 40536

Owensboro

Owensboro Health Mitchell Memorial Cancer Center, Owensboro, Kentucky, United States, 42303

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

For general information about clinical research, read Learn About Studies.

Eligibility Criteria

  • * newly diagnosed or recurrent tobacco related malignancy
  • * smoked at least 1 cigarette within 4 weeks of study enrollment
  • * 10-pack year history of cigarette smoking
  • * smoked at least 1 cigarette within 1 month of cancer diagnosis
  • * life expectancy greater than 1 year
  • * allergy to buproprion, varenicline and transdermal medicine
  • * history of suicide attempt
  • * hospitalized for psychiatric illness within past 2 years
  • * history of active or uncontrolled eating disorder
  • * uncontrolled epilepsy or seizure disorder
  • * pregnant or lactating
  • * within 3 months of myocardial infarction
  • * unstable angina
  • * uncontrolled hypertension
  • * serious arrhythmia
  • * history of taking varenicline or buproprion within one month of enrollment
  • * concurrent enrollment in tobacco cessation therapy

Ages Eligible for Study

18 Years to

Sexes Eligible for Study

ALL

Accepts Healthy Volunteers

No

Collaborators and Investigators

Joseph Valentino, MD,

Joseph Valentino, MD, PRINCIPAL_INVESTIGATOR, University of Kentucky

Study Record Dates

2026-01