Home Based Infusions for Ocrelizumab

Eligibility Criteria

• * Current active patient of Rocky Mountain MS Center at the time of final study consent.
• * Between 18-55 years of age at the time of final study consent.
• * Diagnosis of primary progressive or relapsing MS as defined by the 2017 McDonald criteria.19
• * Has at minimum completed their first 600 mg dose of ocrelizumab.
• * Is physically residing in the Denver metro, Fort Collins or Colorado Springs area at the time of final study consent.
• * Has a Patient Determined Disease Steps (PDDS) between 0 to 6.5 20
• * Can complete patient reported outcomes developed and validated as English written scales.
• * Must be able and willing to give meaningful, informed consent via electronic signature prior to participation in the study, in accordance with local and FDA regulatory requirements.
• * Whose treating neurologist at the RMMSC feels that continuing ocrelizumab s medically appropriate based on at the time of final study consent.
• * Not pregnant, intentions to get pregnant or lactating at the time of final study consent and on the day of infusion.
• * Has previously not participated in the SaROD trial at the RMMSC site.
• * Any of the following abnormal laboratory results as processed by a University of Colorado Hospital laboratory site and deemed clinically inappropriate to proceed with a home infusion by the treating neurologist at RMMSC.