Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.
For general information about clinical research, read Learn About Studies.
Eligibility Criteria
- * Age ≥18 years of age.
- * Suspected newly-diagnosed GBM, World Health Organization (WHO) Grade IV with intent for gross total resection (as defined above).
- * Accessibility for treatment and follow up.
- * Patient consent obtained according to Duke institutional policy.
- * Women of child bearing potential (WOCBP) must have a negative serum pregnancy test according to standard of care prior to surgery.
- * Prior therapy (other than steroids or stereotactic biopsy) or concomitant immunotherapy.
- * Pregnant or breast-feeding during the study period.
- * Patients with an active infection, or febrile within 24 hours of surgery.
- * Patients with inflammatory bowel disease, systemic lupus erythematosus, rheumatoid arthritis, or other autoimmune disease.
- * Patients with history of or active hematologic or bone marrow diseases, including but not limited to diagnosed lymphomas, leukemias, sickle cell or other anemias not associated with their current condition or polycythemia vera.
- * Prior bone marrow harvests preceding this study.
- * Patients with known or suspected immunodeficiency or human immunodeficiency virus (HIV).
- * Hematocrit \< 24 % pre-operatively.
- * Patients with a serious active infection or other serious underlying medical conditions that would impair the ability of the patient to receive protocol treatment or comply with protocol.
Ages Eligible for Study
18 Years to
Sexes Eligible for Study
ALL
Accepts Healthy Volunteers
No