TERMINATED

Effects of Oral Cancer Treatments on Upper Esophageal Opening During Swallowing

Conditions

Cancer of Head and Neck quality of life swallowing outcomes oral cancer

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Study Overview

This clinical trial focuses on testing the efficacy of different digital interventions to promote re-engagement in cancer-related long-term follow-up care for adolescent and young adult (AYA) survivors of childhood cancer.

Description

The purpose of this study is to investigate post-operative and post-radiation upper esophageal sphincter opening measures in oral cancer patients, compare measures to age- and gender-matched healthy adults, and determine relationships with patient swallowing outcomes and quality of life.

Official Title

Effects of Oral Cancer Treatments on Upper Esophageal Opening During Swallowing

Quick Facts

Study Start:2021-04-16

Study Completion:2023-03-25

Study Type:Not specified

Phase:Not Applicable

Enrollment:Not specified

Status:TERMINATED

Study ID

NCT04658342

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Ages Eligible for Study:18 Years

Sexes Eligible for Study:ALL

Accepts Healthy Volunteers:No

Standard Ages:ADULT, OLDER_ADULT

Inclusion Criteria	Exclusion Criteria
* Oral cancer that includes tongue or floor of mouth clinical stage T1 or higher * May have disease that extends to base of tongue or other site as long as floor of mouth or tongue are involved * Adults at least 18 years of age	* Oral cancer of the lip, cheek, palate or other site not impacting tongue or floor of mouth musculature * History of floor of mouth, tongue base, pharyngeal or laryngeal surgical resection * History of radiation treatment to the head and neck * History of dysphagia prior to onset of oral cancer symptoms * Allergy to lidocaine, barium, adhesive tape or apple flavoring * Woman of childbearing years who are pregnant

Inclusion Criteria

Exclusion Criteria

* Oral cancer that includes tongue or floor of mouth clinical stage T1 or higher
* May have disease that extends to base of tongue or other site as long as floor of mouth or tongue are involved
* Adults at least 18 years of age

* Oral cancer of the lip, cheek, palate or other site not impacting tongue or floor of mouth musculature
* History of floor of mouth, tongue base, pharyngeal or laryngeal surgical resection
* History of radiation treatment to the head and neck
* History of dysphagia prior to onset of oral cancer symptoms
* Allergy to lidocaine, barium, adhesive tape or apple flavoring
* Woman of childbearing years who are pregnant

Contacts and Locations

Principal Investigator

Susan Thibeault, PhD

PRINCIPAL_INVESTIGATOR

University of Wisconsin, Madison

Study Locations (Sites)

University of Wisconsin

Madison, Wisconsin, 53792

United States

Collaborators and Investigators

Sponsor: University of Wisconsin, Madison

Susan Thibeault, PhD, PRINCIPAL_INVESTIGATOR, University of Wisconsin, Madison

Study Record Dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Registration Dates

Study Start Date2021-04-16

Study Completion Date2023-03-25

Study Record Updates

Study Start Date2021-04-16

Study Completion Date2023-03-25

Terms related to this study

Keywords Provided by Researchers

quality of life
swallowing outcomes
oral cancer

Additional Relevant MeSH Terms

Cancer of Head and Neck