Evaluating the Bacterial and Fungal Microbiome in Patients With Calcium Oxalate Urolithiasis and Renal Cell Carcinoma

Description

The purpose of the study is to identify bacterial and fungal microbiome associated with calcium oxalate (CO) urolithiasis and renal cell carcinoma (RCC).

Conditions

Calcium Oxalate Urolithiasis, Renal Cell Carcinoma

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Study Overview

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Study Details

Study overview

The purpose of the study is to identify bacterial and fungal microbiome associated with calcium oxalate (CO) urolithiasis and renal cell carcinoma (RCC).

Evaluating the Bacterial and Fungal Microbiome in Patients With Calcium Oxalate Urolithiasis and Renal Cell Carcinoma.

Evaluating the Bacterial and Fungal Microbiome in Patients With Calcium Oxalate Urolithiasis and Renal Cell Carcinoma

Condition
Calcium Oxalate Urolithiasis
Intervention / Treatment

-

Contacts and Locations

Miami

University of Miami, Miami, Florida, United States, 33136

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

For general information about clinical research, read Learn About Studies.

Eligibility Criteria

  • * Adults that are able to consent (≥ 18 years of age)
  • * No history of asymptomatic bacteriuria or Urinary Tract Infection within the past 1 month
  • * No history of coagulopathy and not on anticoagulant or antiplatelet medication at the time of surgery.
  • * For patients with urolithiasis, must not have a history of RCC
  • * For patients with RCC, must not have a history of urolithiasis
  • * Controls must have no history of stones, RCC, or urinary tract infection (within 1 month).
  • * For all participants, no antimicrobial treatment within the past month
  • * Adults unable to consent
  • * For patients with urolithiasis, technical difficulty in taking renal papillae biopsy.
  • * History of urinary tract infection within the past 1 month
  • * History of coagulopathy and on anticoagulants or antiplatelets that could not be stopped perioperatively.
  • * Patients with nephrolithiasis and renal tumors with positive preoperative urine cultures- suggesting asymptomatic bacteriuria.
  • * For patients with urolithiasis, a history of RCC
  • * For patients with RCC, a history of urolithiasis
  • * Controls who have a history of stones, RCC, or urinary tract infection.
  • * For all participants, antimicrobial treatment within the past month.

Ages Eligible for Study

18 Years to

Sexes Eligible for Study

ALL

Accepts Healthy Volunteers

Yes

Collaborators and Investigators

University of Miami,

Hemendra N Shah, PRINCIPAL_INVESTIGATOR, University of Miami

Study Record Dates

2027-01-01