RECRUITING

Mechanistic Interventions and Neuroscience of Dissociation

Study Overview

This clinical trial focuses on testing the efficacy of different digital interventions to promote re-engagement in cancer-related long-term follow-up care for adolescent and young adult (AYA) survivors of childhood cancer.

Description

The purpose of this study is to test the neurophysiological mechanisms of an intervention to reduce symptoms of dissociation in traumatized people. The intervention will be tested in dissociative traumatized people at two sites: Emory University and University of Pittsburgh. The researchers are interested in whether neural networks associated with attentional control and interoceptive awareness can be enhanced in this population. The researchers propose to evaluate whether different body-focused and non-body focused interventions can change these mechanisms.

Official Title

Mechanistic Interventions and Neuroscience of Dissociation

Quick Facts

Study Start:2021-09-18
Study Completion:2026-01-31
Study Type:Not specified
Phase:Not Applicable
Enrollment:Not specified
Status:RECRUITING

Study ID

NCT04670640

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Ages Eligible for Study:18 Years to 65 Years
Sexes Eligible for Study:ALL
Accepts Healthy Volunteers:No
Standard Ages:ADULT, OLDER_ADULT
Inclusion CriteriaExclusion Criteria
  1. * experience of at least one Diagnostic and Statistical Manual of Mental Disorders (DSM-5) Criterion A trauma (assessed using the Life Events Checklist)
  2. * a score of 7 or higher on the Multiscale Dissociation Inventory (MDI) depersonalization subscale
  3. * willingness to participate in the study
  1. * actively psychotic and cognitively compromised individuals (assessed using the Moderate-severe cognitive impairment screening tool (MoCA) will be excluded
  2. * moderate or more severe substance dependence (assessed with the MINI)
  3. * persons with imminent risk of physical violence to self or others

Contacts and Locations

Study Contact

Negar Fani, PhD
CONTACT
404-712-0354
nfani@emory.edu
Greg Siegle, PhD
CONTACT
412-864-3501
gsiegle@pitt.edu

Principal Investigator

Negar Fani, PhD
PRINCIPAL_INVESTIGATOR
Emory University
Greg Siegle, PhD
PRINCIPAL_INVESTIGATOR
University of Pittsburgh

Study Locations (Sites)

Grady Hospital
Atlanta, Georgia, 30303
United States
Western Psychiatric Institute and Clinic
Pittsburgh, Pennsylvania, 15213
United States

Collaborators and Investigators

Sponsor: Emory University

  • Negar Fani, PhD, PRINCIPAL_INVESTIGATOR, Emory University
  • Greg Siegle, PhD, PRINCIPAL_INVESTIGATOR, University of Pittsburgh

Study Record Dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Registration Dates

Study Start Date2021-09-18
Study Completion Date2026-01-31

Study Record Updates

Study Start Date2021-09-18
Study Completion Date2026-01-31

Terms related to this study

Keywords Provided by Researchers

  • Trauma
  • PTSD
  • Mindfulness
  • Meditation
  • Neuroimaging
  • MRI

Additional Relevant MeSH Terms

  • Dissociation