Diabetic Neuropathy in Spinal Cord Stimulator Patients

Description

The objective of this study is to assess the effect Spinal Cord Stimulators have toward improving vascular changes of diabetes mellitus in patients eligible for SCS placement based on their condition of painful diabetic neuropathy; we will evaluate improving their disability and quality of life, improving micro-circulatory changes induced by Diabetes Mellitus (DM), improving macro-circulatory changes induced by DM and improving arterial stiffness of the vessels of the lower extremity.

Conditions

Diabetes Mellitus, Neuropathy, Neuropathic Pain, Vascular Diseases, Vascular Stiffness, Microvascular Changes, Pain, Chronic

Study Overview

Study Details

Study overview

The objective of this study is to assess the effect Spinal Cord Stimulators have toward improving vascular changes of diabetes mellitus in patients eligible for SCS placement based on their condition of painful diabetic neuropathy; we will evaluate improving their disability and quality of life, improving micro-circulatory changes induced by Diabetes Mellitus (DM), improving macro-circulatory changes induced by DM and improving arterial stiffness of the vessels of the lower extremity.

Spinal Cord Stimulation Improves Pain, Arterial Stiffness and Vascular Flow in Lower Extremities in Patients With Diabetes Mellitus Type II A Multidisciplinary Collaborative Prospective Study

Diabetic Neuropathy in Spinal Cord Stimulator Patients

Condition
Diabetes Mellitus
Intervention / Treatment

-

Contacts and Locations

Chicago

University of Chicago Medical Center, Chicago, Illinois, United States, 60637

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

For general information about clinical research, read Learn About Studies.

Eligibility Criteria

  • 1. Patients with DM type 2 of more than 1-year duration
  • 2. DM stage 3 or less
  • 3. Patients ≥18 years of age
  • 4. Refractory painful diabetic peripheral neuropathy of the lower extremities
  • 5. ABI index \<0.9
  • 1. Patients on anticoagulants
  • 2. Patients with active infections
  • 3. Patients with HbA1\>10
  • 4. Psychiatric disorders and cognitive dysfunctions
  • 5. Illicit Drug Usage
  • 6. Patients on dialysis
  • 7. BMI\>35.0
  • 8. Surgery within the last 30 days
  • 9. Ulcer of the lower extremities
  • 10. Calcification of the peripheral arteries

Ages Eligible for Study

18 Years to

Sexes Eligible for Study

ALL

Accepts Healthy Volunteers

No

Collaborators and Investigators

University of Chicago,

Magdalena Anitescu, MD, PhD, PRINCIPAL_INVESTIGATOR, University of Chicago

Study Record Dates

2026-12-01