RECRUITING

Project THINK: Trajectories of Health, Ingestive Behaviors, and Neurocognition in Kids

Study Overview

This clinical trial focuses on testing the efficacy of different digital interventions to promote re-engagement in cancer-related long-term follow-up care for adolescent and young adult (AYA) survivors of childhood cancer.

Description

Overweight/obesity and loss of control eating (characterized by the sense that one cannot control what or how much one is eating) are prevalent among children and adolescents, and both are associated with serious medical and psychosocial health complications. Although our recently published data suggest that youth with these conditions may have relative deficits in neurocognitive functioning, particularly working memory, understanding of how these processes and their neural correlates are related to change and stability in eating and weight-related outcomes over time is limited, thereby impeding development of targeted, optimally timed interventions. The present study aims to assess prospective associations between general and food-specific executive functioning and underlying neural substrates, and eating and weight outcomes among children at varying levels of risk overweight/obesity and eating disorders, which will help guide research efforts towards the development of effective prevention and intervention strategies.

Official Title

Executive Functioning, Weight Trajectories, and Loss of Control Eating in Children With Overweight/Obesity: A Prospective Study

Quick Facts

Study Start:2020-12-10
Study Completion:2025-12-09
Study Type:Not specified
Phase:Not Applicable
Enrollment:Not specified
Status:RECRUITING

Study ID

NCT04701671

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Ages Eligible for Study:9 Years to 12 Years
Sexes Eligible for Study:ALL
Accepts Healthy Volunteers:Yes
Standard Ages:CHILD
Inclusion CriteriaExclusion Criteria
  1. * Not currently taking any medications known to affect weight or appetite
  2. * Free of any current or past medical or psychiatric conditions known to significantly affect eating or weight (e.g., diabetes, bulimia nervosa), with the exception of binge eating disorder
  3. * In the low average range or higher on measures of general intellectual functioning
  4. * Free of any conditions affecting executive functioning (e.g., recent concussion, history of traumatic brain injury)
  5. * Fluent in English, and able to read and comprehend study materials
  6. * Not currently pregnant
  1. Pregnancy or breastfeeding
  2. Severe psychiatric disorders
  3. Active substance abuse
  4. Unstable medical conditions
  5. Inability to comply with study requirements

Contacts and Locations

Study Contact

Erin Stalvey, B.S.
CONTACT
412-586-9066
stalveyer@upmc.edu
Dayna Winograd, B.S.
CONTACT
412-586-9082
bitelab@upmc.edu

Principal Investigator

Andrea B. Goldschmidt, Ph.D.
PRINCIPAL_INVESTIGATOR
University of Pittsburgh

Study Locations (Sites)

University of PIttsburgh
Pittsburgh, Pennsylvania, 15213
United States
Weight Control & Diabetes Research Center
Providence, Rhode Island, 02903
United States

Collaborators and Investigators

Sponsor: University of Pittsburgh

  • Andrea B. Goldschmidt, Ph.D., PRINCIPAL_INVESTIGATOR, University of Pittsburgh

Study Record Dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Registration Dates

Study Start Date2020-12-10
Study Completion Date2025-12-09

Study Record Updates

Study Start Date2020-12-10
Study Completion Date2025-12-09

Terms related to this study

Keywords Provided by Researchers

  • Loss of Control Eating
  • Executive Functioning
  • Pubertal Development

Additional Relevant MeSH Terms

  • Pediatric Obesity
  • Binge-Eating Disorder