RECRUITING

University of Pittsburgh Brain Health Initiative

Talk to us

Conditions

Traumatic Brain InjuryBrain HealthFootballContact SportConcussion

Quick Navigation

Study Overview

This clinical trial focuses on testing the efficacy of different digital interventions to promote re-engagement in cancer-related long-term follow-up care for adolescent and young adult (AYA) survivors of childhood cancer.

Description

This project will define the prevalence of brain health (i.e., normal cognitive, neuromotor, behavioral function) in living professional football retirees and group-matched controls through a comprehensive assessment of clinical, neuroimaging, and biomarker measures.

Official Title

Prevalence of Brain Health Versus Neurodegeneration in Former Professional Football Players

Quick Facts

Study Start:2019-11-18
Study Completion:2025-12
Study Type:Not specified
Phase:Not Applicable
Enrollment:Not specified
Status:RECRUITING

Study ID

NCT04708613

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Ages Eligible for Study:29 Years to 59 Years
Sexes Eligible for Study:MALE
Accepts Healthy Volunteers:Yes
Standard Ages:ADULT
Inclusion CriteriaExclusion Criteria
  1. 1. Professional football retiree aged 29-59
  2. 2. Played a minimum of 3 professional football seasons, with a minimum of 3 games in each season
  3. 3. Fluent in English (translations are not available/validated for most neuropsychological tests)
  4. 1. Age 29-59 male
  5. 2. High school education or beyond
  6. 3. Fluent in English (translations are not available/validated for most neuropsychological tests)
  1. 1. Played organized football beyond high school
  2. 2. History of severe TBI
  3. 3. Current unstable cardiovascular disorder
  4. 1. Prior history of psychosis (such as schizophrenia), or other major neurological disorder that would interfere with testing, in the opinion of the primary investigator.
  5. 2. Contraindication to MR imaging, such as ferrous metal, pacemakers, or concerns about claustrophobia

Contacts and Locations

Study Contact

Kathryn L Edelman, MS
CONTACT
412-624-1077
dunfeekl@upmc.edu

Principal Investigator

David O Okonkwo, MD, PhD
PRINCIPAL_INVESTIGATOR
University of Pittsburgh Department of Neurological Surgery

Study Locations (Sites)

University of Pittsburgh Department of Neurosurgery
Pittsburgh, Pennsylvania, 15213
United States

Collaborators and Investigators

Sponsor: David Okonkwo, MD, PhD

  • David O Okonkwo, MD, PhD, PRINCIPAL_INVESTIGATOR, University of Pittsburgh Department of Neurological Surgery

Study Record Dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Registration Dates

Study Start Date2019-11-18
Study Completion Date2025-12

Study Record Updates

Study Start Date2019-11-18
Study Completion Date2025-12

Terms related to this study

Keywords Provided by Researchers

  • Brain Health
  • Football
  • Contact Sport
  • Concussion

Additional Relevant MeSH Terms

  • Traumatic Brain Injury