RECRUITING

Corticostriatal Contributions to Parkinson's Disease Cognitive Impairment

Study Overview

This clinical trial focuses on testing the efficacy of different digital interventions to promote re-engagement in cancer-related long-term follow-up care for adolescent and young adult (AYA) survivors of childhood cancer.

Description

The goal of this study is to learn more about the brain activity underlying Parkinson's disease cognitive impairment. The investigators will utilize neural recordings from corticostriatal structures performed during deep brain stimulation surgery to measure neural activity underlying nonmotor symptoms of Parkinson's disease.

Official Title

Corticostriatal Neurophysiology in Parkinson's Disease Cognitive Impairment

Quick Facts

Study Start:2021-06-02
Study Completion:2026-02
Study Type:Not specified
Phase:Not Applicable
Enrollment:Not specified
Status:RECRUITING

Study ID

NCT04715984

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Ages Eligible for Study:40 Years
Sexes Eligible for Study:ALL
Accepts Healthy Volunteers:No
Standard Ages:ADULT, OLDER_ADULT
Inclusion CriteriaExclusion Criteria
  1. * Scheduled to undergo deep brain stimulation surgery under local anesthesia at Vanderbilt University Medical Center
  2. * Planned clinical electrode trajectory that contacts caudate
  3. * Age greater than or equal to 40
  4. * Diagnosis of Parkinson's disease
  5. * Able to participate in intraoperative testing
  6. * English speaking
  1. * Age less than 40
  2. * Not able to participate in intraoperative testing (for example unable to comprehend instructions or follow directions)
  3. * Movement disorder other than Parkinson's disease

Contacts and Locations

Study Contact

Sarah Bick, MD
CONTACT
615-322-1883
Sarah.Bick@vumc.org
Helen Qian, BA
CONTACT
h.qian@vumc.org

Principal Investigator

Sarah Bick, MD
PRINCIPAL_INVESTIGATOR
Vanderbilt University Medical Center

Study Locations (Sites)

Vanderbilt University Medical Center
Nashville, Tennessee, 37232
United States

Collaborators and Investigators

Sponsor: Vanderbilt University Medical Center

  • Sarah Bick, MD, PRINCIPAL_INVESTIGATOR, Vanderbilt University Medical Center

Study Record Dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Registration Dates

Study Start Date2021-06-02
Study Completion Date2026-02

Study Record Updates

Study Start Date2021-06-02
Study Completion Date2026-02

Terms related to this study

Keywords Provided by Researchers

  • Deep Brain Stimulation

Additional Relevant MeSH Terms

  • Parkinson Disease