RECRUITING

Neural Correlates of Psychiatric Disorders

Study Overview

This clinical trial focuses on testing the efficacy of different digital interventions to promote re-engagement in cancer-related long-term follow-up care for adolescent and young adult (AYA) survivors of childhood cancer.

Description

This ClincialTrials.gov record originally corresponded to the protocol approved under IRB # 202370. The study was expanded to include stimulation and recordings approved under new IRB #211037. The participant data originally acquired from IRB# 202370 will be included in this new record: This study seeks to better understand the neural activity underlying neuro cognitive disorders. Resting state local field potential recordings will be collected from medically refractory epilepsy patients implanted with depth electrodes for seizure localization, and metrics of neural activity will be correlated with psychiatric symptoms as measured from questionnaires. Subjects will also participate in neuro cognitive tasks while neural recordings are performed, and/or receive neural stimulation through implanted depth electrodes. A better understanding of disordered neural activity underlying neuropsychiatric disorders may additionally contribute to novel methods for diagnosing, treating, and preventing these diseases.

Official Title

Neural Correlates of Neuropsychiatric Functions

Quick Facts

Study Start:2021-03-31
Study Completion:2026-02
Study Type:Not specified
Phase:Not Applicable
Enrollment:Not specified
Status:RECRUITING

Study ID

NCT04725409

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Ages Eligible for Study:18 Years
Sexes Eligible for Study:ALL
Accepts Healthy Volunteers:No
Standard Ages:ADULT, OLDER_ADULT
Inclusion CriteriaExclusion Criteria
  1. * Undergoing SEEG monitoring at Vanderbilt University Medical Center
  2. * At least 18 years of age
  3. * English speaking
  1. * Age \<18
  2. * Not able to complete questionnaires (e.g., unable to comprehend instructions or follow directions)

Contacts and Locations

Study Contact

Sarah Bick, MD
CONTACT
615-322-1883
Sarah.Bick@vumc.org
Helen Qian, BA
CONTACT
h.qian@vumc.org

Principal Investigator

Sarah Bick, MD
PRINCIPAL_INVESTIGATOR
Vanderbilt University Medical Center

Study Locations (Sites)

Vanderbilt University Medical Center
Nashville, Tennessee, 37232
United States

Collaborators and Investigators

Sponsor: Vanderbilt University Medical Center

  • Sarah Bick, MD, PRINCIPAL_INVESTIGATOR, Vanderbilt University Medical Center

Study Record Dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Registration Dates

Study Start Date2021-03-31
Study Completion Date2026-02

Study Record Updates

Study Start Date2021-03-31
Study Completion Date2026-02

Terms related to this study

Keywords Provided by Researchers

  • Depression
  • Stereo Electroencephalography (SEEG)
  • Anxiety
  • Obsessive compulsive disorder
  • Impulsivity
  • Memory

Additional Relevant MeSH Terms

  • Psychiatric Disorder
  • Memory Disorders