Dexmedetomidine for Intraoperative Shivering in Scheduled Elective Cesarean Delivery

Description

The purpose of this study is to determine the optimum dose of Dexmedetomidine to stop shivering in 90% of patients who experience shivering during scheduled elective cesarean deliveries.

Conditions

Shivering, Dose Finding Study

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Study Overview

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Study Details

Study overview

The purpose of this study is to determine the optimum dose of Dexmedetomidine to stop shivering in 90% of patients who experience shivering during scheduled elective cesarean deliveries.

Dexmedetomidine for Treatment of Shivering During Scheduled Elective Cesarean Delivery: Determining the Optimal Dose

Dexmedetomidine for Intraoperative Shivering in Scheduled Elective Cesarean Delivery

Condition
Shivering
Intervention / Treatment

-

Contacts and Locations

Rochester

Mayo Clinic in Rochester, Rochester, Minnesota, United States, 55905

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

For general information about clinical research, read Learn About Studies.

Eligibility Criteria

  • * Women presenting for planned cesarean delivery.
  • * American Society of Anesthesiology Physical Classification Status 2 or 3; without major medical co-morbidities.
  • * Singleton gestation in the 3rd trimester (28-42 weeks gestation).
  • * Spinal anesthesia technique Women presenting for planned cesarean delivery.
  • * American Society of Anesthesiology Physical Classification Status 2 or 3; without major medical co-morbidities.
  • * Singleton gestation in the 3rd trimester (28-42 weeks gestation).
  • * Spinal anesthesia technique.
  • * Any contraindication to spinal anesthesia technique.
  • * Allergy or intolerance to dexmedetomidine or clonidine.
  • * Oral temperature \< 36° Celsius prior to procedure.
  • * Unable to give personal consent.
  • * PPROM or concern for infection (e.g., chorioamnionitis).
  • * Conversion to General Anesthesia prior to randomization.
  • * Sedative medications (e.g., fentanyl, midazolam, ketamine, nitrous oxide) administered prior to randomization.

Ages Eligible for Study

18 Years to

Sexes Eligible for Study

FEMALE

Accepts Healthy Volunteers

No

Collaborators and Investigators

Mayo Clinic,

Hans Sviggum, MD, PRINCIPAL_INVESTIGATOR, Mayo Clinic

Study Record Dates

2025-08