Neurostimulation for Treatment of Chronic Upper Limb Pain After Brachial Plexus Injury

Description

The purpose of this study is to see how much pain intensity is affected by high frequency spinal cord stimulation therapy in individuals with serious brachial plexus injury.

Conditions

Brachial Plexus Injury

Study Overview

Study Details

Study overview

The purpose of this study is to see how much pain intensity is affected by high frequency spinal cord stimulation therapy in individuals with serious brachial plexus injury.

High Frequency Spinal Cord Stimulation for Neuropathic Pain Following Brachial Plexus Avulsion Injury: a Prospective Observational Cohort Study

Neurostimulation for Treatment of Chronic Upper Limb Pain After Brachial Plexus Injury

Condition
Brachial Plexus Injury
Intervention / Treatment

-

Contacts and Locations

Jacksonville

Mayo Clinic, Jacksonville, Florida, United States, 32224

Rochester

Mayo Clinic in Rochester, Rochester, Minnesota, United States, 55905

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

For general information about clinical research, read Learn About Studies.

Eligibility Criteria

  • * Age \> 18 years old
  • * Neuropathic pain of the upper limb ≥ 3 months following brachial plexus avulsion injury.
  • * Patients must be planned to undergo implantation of high-frequency spinal cord stimulation for the treatment of chronic neuropathic pain due to brachial plexus avulsion injury.
  • * Pain that is non-neuropathic as defined by DN4 score \<4.
  • * Pregnant at the time of consideration for implant or planning to become pregnant during the study duration.
  • * Active substance use disorder of any kind.
  • * Active tobacco use.
  • * Use of moderate or high dose opioid medication (oral morphine equivalents \>100 mg daily).
  • * Active, untreated major psychiatric disorder that might interfere with subject's ability to participate.
  • * Involvement in active litigation related to injury.
  • * Patient has not undergone conservative medical management for at least 3 months (including physical and/or occupational therapy and at least one trial of neuropathic pain medication).

Ages Eligible for Study

18 Years to

Sexes Eligible for Study

ALL

Accepts Healthy Volunteers

No

Collaborators and Investigators

Mayo Clinic,

Christy Hunt, DO, PRINCIPAL_INVESTIGATOR, Mayo Clinic

Study Record Dates

2025-12