Detection of Small Fiber Neuropathy Using Skin Properties

Description

Small fiber neuropathy affects millions of peoples worldwide. The neuropathy is causing disabling burning pain and dysautonomia such as dizziness with standing, brain fog, fatigue, constipation, too much or too little sweating. The detection of nerve damage is complicated and not widely available; it requires either skin biopsy or specialized equipment and training. This project utilizes the mathematical processing of skin pictures for the purpose to extract the statistical features related to loss of small fibers. This approach can improve the availability of diagnosis of small fiber neuropathy.

Conditions

Small Fiber Neuropathy

Study Overview

Study Details

Study overview

Small fiber neuropathy affects millions of peoples worldwide. The neuropathy is causing disabling burning pain and dysautonomia such as dizziness with standing, brain fog, fatigue, constipation, too much or too little sweating. The detection of nerve damage is complicated and not widely available; it requires either skin biopsy or specialized equipment and training. This project utilizes the mathematical processing of skin pictures for the purpose to extract the statistical features related to loss of small fibers. This approach can improve the availability of diagnosis of small fiber neuropathy.

Detection of Small Fiber Neuropathy Using Skin Properties

Detection of Small Fiber Neuropathy Using Skin Properties

Condition
Small Fiber Neuropathy
Intervention / Treatment

-

Contacts and Locations

Boston

Brigham and Women's Faulkner Hospital, Boston, Massachusetts, United States, 02130

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

For general information about clinical research, read Learn About Studies.

Eligibility Criteria

  • * Patients with age 18 year or older
  • * Patients that sign the informed consent form to participate in this study
  • * Patients completed the autonomic testing with skin biopsies
  • * Patients with significant hairs at the legs that will cover the skin
  • * Any dermatological disorder that can affect the skin composition
  • * The use of skin lotion

Ages Eligible for Study

18 Years to

Sexes Eligible for Study

ALL

Accepts Healthy Volunteers

No

Collaborators and Investigators

Brigham and Women's Hospital,

Study Record Dates

2025-02-01