RECRUITING

Loupe-Based Intraoperative Fluorescence Imaging

Study Overview

This clinical trial focuses on testing the efficacy of different digital interventions to promote re-engagement in cancer-related long-term follow-up care for adolescent and young adult (AYA) survivors of childhood cancer.

Description

Glioblastoma multiforme (GBM) and anaplastic astrocytoma (AA) are the most common primary malignant brain tumors. Survival of patients with these brain tumors is directly related to the extent of resection. Consequently, a great deal of effort has been directed at developing techniques and technologies that allow more extensive, safe resections. This study will test a loupe-based wearable device in the clinical setting and compare its accuracy with a large operative microscope to identify tumor tissues. Postoperative histopathological analysis on tumor tissues will be used as gold standards for comparison. The outcome from this study will be a low-cost, miniaturized, easy-to-operate, loupe-based fluorescence imaging device for intraoperative guidance of brain tumor resection with the same level of accuracy as the large microscope.

Official Title

Loupe-Based Intraoperative Fluorescence Imaging for the Guidance of Brain Tumor Surgery

Quick Facts

Study Start:2017-11-17
Study Completion:2026-06
Study Type:Not specified
Phase:Not Applicable
Enrollment:Not specified
Status:RECRUITING

Study ID

NCT04780009

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Ages Eligible for Study:18 Years to 90 Years
Sexes Eligible for Study:ALL
Accepts Healthy Volunteers:No
Standard Ages:ADULT, OLDER_ADULT
Inclusion CriteriaExclusion Criteria
  1. * adults with brain malignant gliomas undergoing resection
  2. * at least 18 years of age
  3. * able to understand the consent
  1. * pregnant women
  2. * under 18 years of age
  3. * patients undergoing emergency surgery
  4. * inability to give consent due to dysphagia or language barrier

Contacts and Locations

Principal Investigator

Guoqiang Yu, PhD
PRINCIPAL_INVESTIGATOR
University of Kentucky

Study Locations (Sites)

University of Kentucky
Lexington, Kentucky, 40536
United States

Collaborators and Investigators

Sponsor: Guoqiang Yu

  • Guoqiang Yu, PhD, PRINCIPAL_INVESTIGATOR, University of Kentucky

Study Record Dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Registration Dates

Study Start Date2017-11-17
Study Completion Date2026-06

Study Record Updates

Study Start Date2017-11-17
Study Completion Date2026-06

Terms related to this study

Keywords Provided by Researchers

  • fluorescence
  • resection
  • 5-ALA
  • fluorescein
  • optical

Additional Relevant MeSH Terms

  • Glioblastoma Multiforme
  • Anaplastic Astrocytoma