Cannabis Effects on Antiretroviral Therapy Pharmacokinetics and Neurotoxicity

Description

This study will address whether cannabis affects antiretroviral therapy (ART) drug concentrations, mood, and thinking. The project will have two phases. Phase 1 is an observational study, in which 120 people will be assessed to evaluate the effects of chronic cannabis use on ART drug concentrations, mood, and thinking. In Phase 2, the study will administer cannabis (or placebo) to 40 people to examine its acute effects on ART drug concentrations.

Conditions

HIV, Cannabis Use

Study Overview

Study Details

Study overview

This study will address whether cannabis affects antiretroviral therapy (ART) drug concentrations, mood, and thinking. The project will have two phases. Phase 1 is an observational study, in which 120 people will be assessed to evaluate the effects of chronic cannabis use on ART drug concentrations, mood, and thinking. In Phase 2, the study will administer cannabis (or placebo) to 40 people to examine its acute effects on ART drug concentrations.

Cannabis Effects on Antiretroviral Therapy Pharmacokinetics and Neurotoxicity

Cannabis Effects on Antiretroviral Therapy Pharmacokinetics and Neurotoxicity

Condition
HIV
Intervention / Treatment

-

Contacts and Locations

San Diego

Ucsd Hnrp-Cmcr, San Diego, California, United States, 92103

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

For general information about clinical research, read Learn About Studies.

Eligibility Criteria

    Ages Eligible for Study

    18 Years to

    Sexes Eligible for Study

    ALL

    Accepts Healthy Volunteers

    Yes

    Collaborators and Investigators

    University of California, San Diego,

    Scott Letendre, MD, PRINCIPAL_INVESTIGATOR, UCSD

    Study Record Dates

    2025-04-30