RECRUITING

Association of Periodontal Inflammation on Immune Response in Wound Healing

Study Overview

This clinical trial focuses on testing the efficacy of different digital interventions to promote re-engagement in cancer-related long-term follow-up care for adolescent and young adult (AYA) survivors of childhood cancer.

Description

Subjects who are in need of extraction of a posterior tooth will be recruited for this study. Prior to extraction, periodontal clinical markers of inflammation, body-mass index and dental radiographs will be measured/taken. The posterior tooth will be atraumatically extracted and a small soft tissue biopsy of the extraction site will be taken. At the two week follow-up, sutures will be removed and another small biopsy of soft tissue will be taken. Subjects will be seen again at 3 months for a final collection of clinical data and radiographs.

Official Title

Association of Periodontal Inflammation on Immune Response in Wound Healing

Quick Facts

Study Start:2021-09-01
Study Completion:2026-07
Study Type:Not specified
Phase:Not Applicable
Enrollment:Not specified
Status:RECRUITING

Study ID

NCT04805320

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Ages Eligible for Study:21 Years to 70 Years
Sexes Eligible for Study:ALL
Accepts Healthy Volunteers:Yes
Standard Ages:ADULT, OLDER_ADULT
Inclusion CriteriaExclusion Criteria
  1. * non-restorable posterior tooth (molar/premolar) in need of extraction
  1. * systemic disease that effects inflammation

Contacts and Locations

Study Contact

Amy C Killeen, DDS
CONTACT
402-472-7848
akilleen@unmc.edu

Principal Investigator

Joseph B Bavitz, DMD
STUDY_CHAIR
University of Nebraska, College of Dentistry

Study Locations (Sites)

University of Nebraska, College of Dentistry
Lincoln, Nebraska, 68583
United States

Collaborators and Investigators

Sponsor: University of Nebraska

  • Joseph B Bavitz, DMD, STUDY_CHAIR, University of Nebraska, College of Dentistry

Study Record Dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Registration Dates

Study Start Date2021-09-01
Study Completion Date2026-07

Study Record Updates

Study Start Date2021-09-01
Study Completion Date2026-07

Terms related to this study

Keywords Provided by Researchers

  • periodontitis
  • wound healing
  • extraction

Additional Relevant MeSH Terms

  • Inflammation of Mouth